ESAT6
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Official Full Name
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Overview
The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but -
Synonyms
6 kDa early secretory antigenic target;6 kDa early secretory antigenic target ESXA;ESAT 6;esaT6;ESXA
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Involved Pathway
ESAT6 involved in several pathways and played different roles in them. We selected most pathways ESAT6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ESAT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ESAT6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ESAT6 itself. We selected most functions ESAT6 had, and list some proteins which have the same functions with ESAT6. You can find most of the proteins on our site.
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Interacting Protein
ESAT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESAT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ESAT6.
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References
- Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
- Tang, XL; Zhou, YX; et al. CFP10 and ESAT6 aptamers as effective Mycobacterial antigen diagnostic reagents. JOURNAL OF INFECTION 69:569-580(2014).
