ERLIN2
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Official Full Name
ER lipid raft associated 2 -
Overview
Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene. -
Synonyms
ERLIN2;ER lipid raft associated 2;C8orf2, chromosome 8 open reading frame 2 , Erlin 2, SPFH domain family, member 2 , SPFH2;erlin-2;NET32;SPFH domain family, member 2;endoplasmic reticulum lipid raft-associated protein 2;stomatin-prohibitin-floti
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Zebrafish
- zebrafish
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
ERLIN2 involved in several pathways and played different roles in them. We selected most pathways ERLIN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ERLIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ERLIN2 has several biochemical functions, for example, cholesterol binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERLIN2 itself. We selected most functions ERLIN2 had, and list some proteins which have the same functions with ERLIN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | Fzd4,MAGEA2B,HSPA1B,UBE2K,RIPK1,CDKN1A,UBE2J2,FZD6,ATP6V0C,KDM4A |
| cholesterol binding | PMP2,APOA4,APOA1A,NPC1,STAR,TSPO,APOC3,ABCA1,APOA1,PROM2 |
| protein binding | CSTF2T,YES1,LZTS1,SP1,RAB39B,AKR1B10,DNM1,RAB4B,PCOLCE,CACNB2 |
Interacting Protein
ERLIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERLIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERLIN2.
pi3p;15-deoxy-delta(12,14;gcb;Ktn1;FN1;Rab5c;Bmpr1a;RAB7A;STK3;ICT1;Klhl21;Rmdn3;TMEM63B;P;Ufl1;C1qbp;Ppp6r3;NCSTN;HDAC11
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References
- Shi, ST; Lee, KJ; et al. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that coffactionates with caveolin-2. JOURNAL OF VIROLOGY 77:4160-4168(2003).
- Dixit, G; Mikoryak, C; et al. Cholera toxin up-regulates endoplasmic reticulum proteins that correlate with sensitivity to the toxin. EXPERIMENTAL BIOLOGY AND MEDICINE 233:163-175(2008).
- Lee, H; Park, DS; et al. Src-induced phosphorylation of caveolin-2 on tyrosine 19 - Phospho-caveolin-2 (Tyr(P)(19)) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1. JOURNAL OF BIOLOGICAL CHEMISTRY 277:34556-34567(2002).
