ERC2

  • Official Full Name

    ELKS/RAB6-interacting/CAST family member 2
  • Overview

    Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
  • Synonyms

    ERC2;ELKS/RAB6-interacting/CAST family member 2;CAST;CAST1;ELKSL;Spc110;SPBC110;ERC protein 2;cytomatrix protein p110;CAZ-associated structural protein

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ERC2-12520H Recombinant Human ERC2, GST-tagged E.coli Human GST 768-827a.a.
ERC2-2136R Recombinant Rat ERC2 Protein Mammalian Cell Rat His
ERC2-5283M Recombinant Mouse ERC2 Protein Mammalian Cell Mouse His
ERC2-6569HCL Recombinant Human ERC2 293 Cell Lysate HEK293 Human Non
ERC2-1793R Recombinant Rat ERC2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ERC2-1793R-B Recombinant Rat ERC2 Protein Pre-coupled Magnetic Beads HEK293 Rat
ERC2-2841M Recombinant Mouse ERC2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ERC2-2841M-B Recombinant Mouse ERC2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ERC2 involved in several pathways and played different roles in them. We selected most pathways ERC2 participated on our site, such as Diurnally regulated genes with circadian orthologs, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Diurnally regulated genes with circadian orthologs QKI,UCP3,TOB1,KLF9,NCKAP1,ZFR,PURA,GFRA1,CBX3,MYF6

    Protein Function

    ERC2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERC2 itself. We selected most functions ERC2 had, and list some proteins which have the same functions with ERC2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding EEF1A1,MRPS23,TTLL6,MSLN,HCST,VPS4B,NFE2L1,HNRNPH3,TOMM7,EREG

    Interacting Protein

    ERC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERC2.

    MYB;IQCB1;Cd2ap

    Resources

    References

    • Arai, E; Sakamoto, H; et al. Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome. INTERNATIONAL JOURNAL OF CANCER 135:1330-1342(2014).
    • Bruin, SC; de Ronde, JJ; et al. Selection of Patients for Hepatic Surgery of Colorectal Cancer Liver Metastasis Based on Genomic Aberrations. ANNALS OF SURGICAL ONCOLOGY 20:S560-S569(2013).

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