EPS8L2
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Official Full Name
EPS8-like 2 -
Overview
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. -
Synonyms
EPS8L2;EPS8-like 2;epidermal growth factor receptor kinase substrate 8-like protein 2;FLJ21935;FLJ22171;MGC3088;EPS8-like protein 2;EPS8-related protein 2;epidermal growth factor receptor pathway substrate 8-related protein 2;EPS8R2;FLJ16738;MG
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
EPS8L2 involved in several pathways and played different roles in them. We selected most pathways EPS8L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EPS8L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
EPS8L2 has several biochemical functions, for example, contributes_to Rac guanyl-nucleotide exchange factor activity,contributes_to Rho guanyl-nucleotide exchange factor activity,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPS8L2 itself. We selected most functions EPS8L2 had, and list some proteins which have the same functions with EPS8L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | TBCCD1,PHACTR4B,SLC4A1,PARK2,INF2,SYN1,CALD1B,WASF1,PLEC,SMYHC3 |
| contributes_to Rho guanyl-nucleotide exchange factor activity | EPS8L1 |
| contributes_to Rac guanyl-nucleotide exchange factor activity | EPS8L1 |
Interacting Protein
EPS8L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPS8L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPS8L2.
LRRK2;CD3E;RPL23;PTK2;TNS2;RIN3;pi3p;SNW1;CDC5L
Resources
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References
- Furness, DN; Johnson, SL; et al. Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:13898-13903(2013).
- Colas, E; Perez, C; et al. Molecular markers of endometrial carcinoma detected in uterine aspirates. INTERNATIONAL JOURNAL OF CANCER 129:2435-2444(2011).
