EPN2
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Official Full Name
epsin 2 -
Overview
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. -
Synonyms
EPN2;epsin 2;epsin-2;EHB21;Eps15 binding protein;KIAA1065;EPS-15-interacting protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EPN2-2017C | Recombinant Chicken EPN2 | Mammalian Cells | Chicken | His |
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| EPN2-3417H | Recombinant Human EPN2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EPN2-6580HCL | Recombinant Human EPN2 293 Cell Lysate | HEK293 | Human | Non |
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| EPN2-3912H | Recombinant Human EPN2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| EPN2-4393HF | Recombinant Full Length Human EPN2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 584 amino acids |
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| Epn2-963M | Recombinant Mouse Epn2 Protein, MYC/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
EPN2 involved in several pathways and played different roles in them. We selected most pathways EPN2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | CYTH2,KIF5A,TFRC,SNX4,HSC70,ASAP2B,CXCR2,VPS45,ARAP2,CCR5 |
Protein Function
EPN2 has several biochemical functions, for example, lipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPN2 itself. We selected most functions EPN2 had, and list some proteins which have the same functions with EPN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | WBP1,AAK1,ACPL2,UCP3,SULT4A1,ALPP,ZNF223,PDCD6IP,GPR143,INS |
| lipid binding | BAX,BAIAP2L2B,FNBP1,YBX2,FABP11A,OSBPL9,STARD8,UNC119.1,APOA4B.2,FFAR2 |
Interacting Protein
EPN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPN2.
GTSE1
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References
- Khanna, R; Li, Q; et al. 'Fractional Recovery' Analysis of a Presynaptic Synaptotagmin 1-Anchored Endocytic Protein Complex. PLOS ONE 1:-(2006).
- Sorkina, T; Miranda, M; et al. RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. JOURNAL OF NEUROSCIENCE 26:8195-8205(2006).
