EPN1
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Official Full Name
epsin 1 -
Overview
The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. -
Synonyms
EPN1;epsin 1;epsin-1;EH domain binding mitotic phosphoprotein;EPN 1;EPS 15 interacting protein 1;EPS-15-interacting protein 1;EH domain-binding mitotic phosphoprotein
Recombinant Proteins
- Zebrafish
- Rat
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
EPN1 involved in several pathways and played different roles in them. We selected most pathways EPN1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | FAM21C,CCR5,SMAP2,ARPC2,WIPF1A,HLA-B,ADRBK2,VPS37B,PRKCI,RAB4A |
Protein Function
EPN1 has several biochemical functions, for example, ion channel binding,lipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPN1 itself. We selected most functions EPN1 had, and list some proteins which have the same functions with EPN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipid binding | UNC119B,AP2M1A,CHMP4A,CRABP2B,CETP,FER,TRIP10,SH3GL1,MARK2,APOEA |
| protein binding | SNAP91,UNC13A,CRIPAK,YWHAB,HSD17B10,CTSL1,PDCD2,NIF3L1,KIF1C,CIB3 |
| transcription factor binding | AIP,JUNB,GATA3,NKX3,CRY1,HDAC3,SMAD3,ESRRB,FOXO1,SOX8 |
| ion channel binding | CALM3,YWHAQ,CTNNB1,FXYD1,CHERP,FYN,CDH5,SLC8A1,KCNC1,HSP90AB1 |
Interacting Protein
EPN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPN1.
REPS2;DAZAP2;PLEKHB2;VCAM1;UBA1;EPS15;UBE2N;UBE2V1;Map3k1;LAPTM5;CRMP1;npr
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References
- Benhra, N; Vignaux, F; et al. Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells. MOLECULAR BIOLOGY OF THE CELL 21:2078-2086(2010).
- Jakobsson, J; Gad, H; et al. Role of epsin 1 in synaptic vesicle endocytosis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:6445-6450(2008).
- Khanna, R; Li, Q; et al. 'Fractional Recovery' Analysis of a Presynaptic Synaptotagmin 1-Anchored Endocytic Protein Complex. PLOS ONE 1:-(2006).
- Han, ZZ; Karatan, E; et al. Accelerated screening of phage-display output with alkaline phosphatase fusions. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 7:55-62(2004).
