ENTPD4
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Official Full Name
ectonucleoside triphosphate diphosphohydrolase 4 -
Overview
This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. -
Synonyms
ENTPD4;ectonucleoside triphosphate diphosphohydrolase 4;LYSAL1, lysosomal apyrase like 1;KIAA0392;LALP70;LAP70;NTPDase 4;UDPase;Apyrase lysosomal;ENTPD 4;Guanosine diphosphatase like protein;LYSAL1;Lysosomal apyrase like 1;Lysosomal apyrase like protein of 70 kDa;Uridine diphosphatase;golgi luminal UDPase;uridine-diphosphatase;lysosomal apyrase-like 1;guanosine-diphosphatase like protein;lysosomal apyrase-like protein of 70 kDa;NTPDase-4
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- Mus musculus
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
ENTPD4 involved in several pathways and played different roles in them. We selected most pathways ENTPD4 participated on our site, such as Purine metabolism,Pyrimidine metabolism,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENTPD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | DCK,PDE6A,POLR1A,POLR3B,POLR1B,PNP6,IMPDH1A,POLR2E,PDE2A,PRPS1B |
| Pyrimidine metabolism | ENTPD1,POLR1E,NME4,POLE4,NME3,NT5C1BA,POLR3E,NT5M,POLR2J3,DHODH |
| Lysosome | AP3M1,IGF2R,SLC11A1,GALC,ATP6V0CA,ATP6V0A1,ASAH1,TPP1,CTSL1B,AP4M1 |
Protein Function
ENTPD4 has several biochemical functions, for example, uridine-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ENTPD4 itself. We selected most functions ENTPD4 had, and list some proteins which have the same functions with ENTPD4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| uridine-diphosphatase activity | ENTPD5,ENTPD6,CANT1,CANT1A,CANT1B |
Interacting Protein
ENTPD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENTPD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENTPD4.
RPS27;metI
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