EMR1
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Official Full Name
EGF-like module containing, mucin-like, hormone receptor-like sequence 1 -
Overview
A monovalent human recombinant Fab selected from the phage display library, expressed in E. coli. The antibody is tagged with a DYKDDDDK tag and a Strep tag at the C-terminus of the antibody heavy chain. This antibody is supplied as a liquid. -
Synonyms
Idiotype;Anti-F4/80;MCA497
Recombinant Proteins
- Human
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EMR1-12443H | Recombinant Human EMR1, GST-tagged | E.coli | Human | GST | 32-346a.a. | |
| EMR1-2097R | Recombinant Rat EMR1 Protein | Mammalian Cell | Rat | His |
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| EMR1-3291H | Recombinant Human EMR1 Protein | Wheat Germ | Human | Non |
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| EMR1-3292H | Recombinant Human EMR1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EMR1-478H | Recombinant Human EMR1 | Mammalian Cell | Human | His |
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| EMR1-554HCL | Recombinant Human EMR1 cell lysate | Human | Non |
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| EMR1-1754R | Recombinant Rat EMR1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| EMR1-1754R-B | Recombinant Rat EMR1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| EMR1-2850H | Recombinant Human EMR1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| EMR1-2850H-B | Recombinant Human EMR1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| EMR1-2952H | Recombinant Human EMR1 Protein (His21-Glu220), His tagged | E.coli | Human | His | His21-Glu220 |
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| EMR1-4271HF | Recombinant Full Length Human EMR1 Protein | In Vitro Cell Free System | Human | Full L. 254 amino acids |
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| EMR1-4272HF | Recombinant Full Length Human EMR1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 821 amino acids |
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Involved Pathway
EMR1 involved in several pathways and played different roles in them. We selected most pathways EMR1 participated on our site, such as Class B/2 (Secretin family receptors),GPCR ligand binding,GPCRs, Class B Secretin-like, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCRs, Class B Secretin-like | EMR2,CALCRL,ADCYAP1R1,CRHR1,LPHN1,CD97,ELTD1,CRHR2 |
| Class B/2 (Secretin family receptors) | PTHLH,RAMP2,EMR4,ADCYAP1,ADM,SCT,FZD10,ADCYAP1B,CRH,CALCRL |
| Signal Transduction | RHOJ,EMR2,LPAR2B,OPN4B,DHRS3A,IFT52,ARHGAP12B,CNGA1,ARHGEF18A,FFAR3 |
| GPCR ligand binding | PNOCB,SSTR3,OXGR1A.1,PENK,CRHR1,CCK,OXGR1A.2,ADORA1,RLN3A,RCA2.1 |
| Signaling by GPCR | TAS2R13,UTS2D,OR52B4,PENKB,OR56A1,KISS1,EMR2,CXCL11.8,OXGR1A.3,SCT |
Protein Function
EMR1 has several biochemical functions, for example, G-protein coupled receptor activity,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMR1 itself. We selected most functions EMR1 had, and list some proteins which have the same functions with EMR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | TGM3,JAG2B,PLCH1,PCDH2AB7,SERPINB1A,PPP3R1B,PLS3,PCLO,LRP2,EFEMP1 |
| G-protein coupled receptor activity | OLFCJ1,CCR12A,TAS2R125,OLFR149,PPYR1,PTGER2B,GPR18,TAAR14H,GNRHR3,OLFCG3 |
Interacting Protein
EMR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMR1.
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References
- Bernard, CE; Gibbons, SJ; et al. Association of low numbers of CD206-positive cells with loss of ICC in the gastric body of patients with diabetic gastroparesis. NEUROGASTROENTEROLOGY AND MOTILITY 26:1275-1284(2014).
- Legrand, F; Tomasevic, N; et al. The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 133:1439-U350(2014).
