ELP2
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Official Full Name
elongation protein 2 homolog -
Overview
Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene. -
Synonyms
ELP2;elongation protein 2 homolog (S. cerevisiae);signal transducer and activator of transcription 3 interacting protein 1 , STATIP1;elongator complex protein 2;FLJ10879;StIP;stIP1;elongator protein 2;STAT3-interacting protein 1;signal transducer
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ELP2-1983H | Recombinant Human ELP2, GST-tagged | Wheat Germ | Human | GST | 1-800 a.a. |
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| ELP2-2082R | Recombinant Rat ELP2 Protein | Mammalian Cell | Rat | His |
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| ELP2-30857TH | Recombinant Human ELP2, His-tagged | E.coli | Human | His | 552-826 a.a. |
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| ELP2-3992H | Recombinant Human ELP2, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| ELP2-4026Z | Recombinant Zebrafish ELP2 | Mammalian Cell | Zebrafish | His |
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| ELP2-5154M | Recombinant Mouse ELP2 Protein | Mammalian Cell | Mouse | His |
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| ELP2-6616HCL | Recombinant Human ELP2 293 Cell Lysate | HEK293 | Human | Non |
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| ELP2-1739R | Recombinant Rat ELP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ELP2-1739R-B | Recombinant Rat ELP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ELP2-2756M | Recombinant Mouse ELP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ELP2-2756M-B | Recombinant Mouse ELP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Elp2-2805M | Recombinant Mouse Elp2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ELP2-7900HFL | Recombinant Full Length Human ELP2, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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Involved Pathway
ELP2 involved in several pathways and played different roles in them. We selected most pathways ELP2 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin organization | MORF4L2,PHF2,MSL2A,C20orf20,KDM2AA,JHDM1D,MSL1A,SUZ12A,C17orf81,DMAP1 |
| HATs acetylate histones | KAT7,MSL3,MBIP,PHF20B,CSRP2BP,ELP4,ELP3,TADA1,BRD1,ING3 |
| Chromatin modifying enzymes | JADE1,MORF4L2,SMARCE1,PHF17,TADA2B,KDM5B,KANSL3,SMARCC2,MORF4L1,PADI6 |
Protein Function
ELP2 has several biochemical functions, for example, contributes_to RNA polymerase II core binding,histone binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELP2 itself. We selected most functions ELP2 had, and list some proteins which have the same functions with ELP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | PRDX3,GATA6,CDC25C,MAPKAP1,FAM83E,CHEK2,CCNT2A,MAP3K13,NCS1,NME2 |
| histone binding | PYGO2,CTSL2,HIST1H4B,APBB1,SFMBT1,HIST4H4,PRKCBP1L,PRMT7,PRMT6,NCAPD3 |
| transcriptional repressor activity, RNA polymerase II transcription factor binding | AHRR,MLIP,EOMES,RIMKLB,T,BHLHE40,PITX2,AHRRA,TBX6,AHRRB |
| contributes_to RNA polymerase II core binding | ELP4,ELP3,IKBKAP |
Interacting Protein
ELP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELP2.
IKBKAP;ETS1;ELP4
Resources
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References
- Srokowski, EM; Woodhouse, KA; et al. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 102:540-551(2014).
- Gu, JX; Sun, DM; et al. Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 41:831-838(2009).
- Liu, WE; Dreher, MR; et al. Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice. JOURNAL OF CONTROLLED RELEASE 116:170-178(2006).
