ELF1

  • Official Full Name

    E74-like factor 1 (ets domain transcription factor)

  • Overview

    This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.

  • Synonyms

    ELF1;E74-like factor 1 (ets domain transcription factor);ETS-related transcription factor Elf-1;mElf 1;E74 like factor 1;ELF 1;Ets domain transcription factor;ETS related transcription factor Elf 1;ETS related transcription factor Elf1;p70;Sts1;TRANSCRIPTION FACTOR ELF 1;OTTHUMP00000018310

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • HIS
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ELF1-12399H Recombinant Human ELF1, GST-tagged E.coli Human GST 320-618a.a.
ELF1-095H Recombinant Human ELF1 Protein, HIS-tagged E.coli Human HIS
ELF1-1416C Recombinant Chicken ELF1 Mammalian Cell Chicken His
ELF1-1438R Recombinant Rhesus monkey ELF1 Protein, His-tagged Mammalian Cell Rhesus macaque His
ELF1-3236H Recombinant Human ELF1 Protein, GST-tagged Wheat Germ Human GST
ELF1-548HCL Recombinant Human ELF1 cell lysate Human Non
ELF1-1262R Recombinant Rhesus Macaque ELF1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ELF1-1262R-B Recombinant Rhesus Macaque ELF1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ELF1-1348HFL Recombinant Full Length Human ELF1 Protein, N-His-tagged E.coli Human His Full L.
ELF1-4341HF Recombinant Full Length Human ELF1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 619 amino acids

    Involved Pathway

    ELF1 involved in several pathways and played different roles in them. We selected most pathways ELF1 participated on our site, such as Angiopoietin receptor Tie2-mediated signaling,IL2 signaling events mediated by STAT5,Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Angiopoietin receptor Tie2-mediated signaling AGTR1,GRB14,BMX,CDKN1A,DOK2,CRK,ELF2,GRB7
    Regulation of retinoblastoma protein CBX4,ATF7,CKM,MYOD1,AATF,SMARCB1,GSC,BGLAP,BRD2

    Protein Function

    ELF1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELF1 itself. We selected most functions ELF1 had, and list some proteins which have the same functions with ELF1. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding LBX1,TBPL2,ZKSCAN3,FOXD4,Aff1,FOXD2,ZFP629,POU6F1,ZNF573,DMRT3A
    protein binding BCS1L,ARMCX1,PRKCA,CCNB1IP1,HES1,LRRC6,PCNP,SLC26A6,FAM161A,FAM20C
    RNA polymerase II core promoter proximal region sequence-specific DNA binding NEUROG3,ZIC3,YBX1,MYBL1,HIST2H3A,ZNF460,DDN,NR1D1,GMEB2,KCNA3
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding CREB3L1,MIXL1,HOXD13,MYOG,ETV2,PLSCR1,POU2F2,SOX12,RBPJ,PITX3

    Interacting Protein

    ELF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELF1.

    HOXC13;SP1;purL;flgE;htrA;q81sn0_bacan;ecfA1;fusA;ligA;mdtA;q9zc29_yerpe;dsdna_dadg:dcdt;BCL6

    Resources

    Research Area

    Adaptor Proteins
    Phosphatases and Regulators
    T Cell Antigen Recognition

    References

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