ELAVL2
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Official Full Name
ELAV like neuron-specific RNA binding protein 2 -
Overview
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3 UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] -
Synonyms
ELAVL2;ELAV like neuron-specific RNA binding protein 2;HUB;HELN1;HEL-N1;ELAV-like protein 2;hu-antigen B;ELAV-like neuronal protein 1 isoform Hel-N2;nervous system-specific RNA-binding protein Hel-N1;ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Yeast
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
ELAVL2 involved in several pathways and played different roles in them. We selected most pathways ELAVL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ELAVL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ELAVL2 has several biochemical functions, for example, mRNA 3-UTR binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELAVL2 itself. We selected most functions ELAVL2 had, and list some proteins which have the same functions with ELAVL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | RAB14L,TMEM63B,SEPT5B,NME2B.2,EWSR1B,ABCD3,NPR1A,TOR1L3,GNA13A,UBE2G1A |
| poly(A) RNA binding | NARG1,MRM1,PEBP1,CSTF2,RPP25L,NCL,HNRNPD,STRBP,RBM39,ZMAT3 |
| protein binding | ZNF180,ARL14,CSF2RA,COG7,ZNF664-FAM101A,STUB1,CRABP1,RRAGB,HADHB,ATP6V1D |
| mRNA 3-UTR binding | IGF2BP2,RNF20,FXR1,PUM1,KHSRP,SERBP1,CSDA,PARN,CPEB1,CPEB2 |
Interacting Protein
ELAVL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELAVL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELAVL2.
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