ELA3B
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Official Full Name
CELA3B chymotrypsin-like elastase family, member 3B -
Overview
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. -
Synonyms
E1;CBPP;EL-1;ELA3B;chymotrypsin-like elastase family member 3B;elastase 1;protease E;elastase-3B;proteinase E;elastase IIIB;fecal elastase 1;OTTHUMP00000002837;pancreatic elastase 1;elastase 3B, pancreatic;pancreatic endopeptidase E;cholesterol-binding pancreatic protease
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Involved Pathway
ELA3B involved in several pathways and played different roles in them. We selected most pathways ELA3B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ELA3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ELA3B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ELA3B itself. We selected most functions ELA3B had, and list some proteins which have the same functions with ELA3B. You can find most of the proteins on our site.
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Interacting Protein
ELA3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELA3B here. Most of them are supplied by our site. Hope this information will be useful for your research of ELA3B.
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