ELA1
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Official Full Name
Ela1p -
Overview
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six;elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other;elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been;detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal;material is actually referring to chymotrypsin-like elastase family, member 3B. -
Synonyms
ELA1;Ela1p;Elo A;EloA;ELOA1_HUMAN;Elongin 110 kDa subunit;Elongin-A;ElonginA;RNA polymerase II transcription factor SIII subunit A1;SIII;SIII p110;TCEB 3;Tceb3;TCEB3A;Transcription elongation factor B (SIII) polypeptide 3 (110kD);Transcription elongation factor B (SIII) polypeptide 3;Transcription elongation factor B alpha subunit;Transcription elongation factor B polypeptide 3;Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21;subunit of the Elongin-Cullin-Socs (ECS) ligase complex
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Involved Pathway
ELA1 involved in several pathways and played different roles in them. We selected most pathways ELA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ELA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ELA1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ELA1 itself. We selected most functions ELA1 had, and list some proteins which have the same functions with ELA1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
ELA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELA1.
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References
- Creff, A; Brocard, L; et al. A mechanically sensitive cell layer regulates the physical properties of the Arabidopsis seed coat. NATURE COMMUNICATIONS 6:-(2015).
- Seleznik, GM; Zoller, J; et al. The role of lymphotoxin signaling in the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies. CYTOKINE & GROWTH FACTOR REVIEWS 25:125-137(2014).
