EIF1
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Official Full Name
eukaryotic translation initiation factor 1 -
Overview
Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. -
Synonyms
EIF1;eukaryotic translation initiation factor 1;A121;ISO1;SUI1;EIF-1;EIF1A;sui1iso1;protein translation factor SUI1 homolog
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- HEK293T
- His
- Myc&DDK
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EIF1-12343H | Recombinant Human EIF1, His-tagged | E.coli | Human | His | 1-113a.a. | |
| EIF1-1840H | Recombinant Human EIF1, His-tagged | E.coli | Human | His |
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| EIF1-388H | Recombinant Human EIF1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| EIF1-4023C | Recombinant Chicken EIF1 | Mammalian Cell | Chicken | His |
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| EIF1-5070M | Recombinant Mouse EIF1 Protein | Mammalian Cell | Mouse | His |
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| EIF1-6679HCL | Recombinant Human EIF1 293 Cell Lysate | HEK293 | Human | Non |
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| EIF1-2695M | Recombinant Mouse EIF1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| EIF1-2695M-B | Recombinant Mouse EIF1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Eif1-2768M | Recombinant Mouse Eif1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EIF1-5216H | Recombinant Human EIF1 protein, GST-tagged | E.coli | Human | GST | 1-113aa |
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Involved Pathway
EIF1 involved in several pathways and played different roles in them. We selected most pathways EIF1 participated on our site, such as RNA transport,Translation Factors, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | BAT1,EEF1A1A,NUP210L,POP5,NXT2,RPP40,UBE2IA,THOC3,NUP133,PAIP1 |
| Translation Factors | EIF2B1,PAIP1,EIF5A,EIF4EBP2,EEF1D,EEF1G,EEF2B,EEF1B2,EEF1A2 |
Protein Function
EIF1 has several biochemical functions, for example, poly(A) RNA binding,translation factor activity, RNA binding,translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF1 itself. We selected most functions EIF1 had, and list some proteins which have the same functions with EIF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation factor activity, RNA binding | EEF1A2,EIF5,GTF2H3,EIF4H,EIF4G3,MTIF3,PPP1R2P9,EIF4G1,EIF4G2,EEF2K |
| poly(A) RNA binding | TWF2,HIST4H4,NMD3,NPM1,IMP3,POP1,PIGC,HNRNPL,UTP3,NUFIP2 |
| translation initiation factor activity | EIF4B,EIF3E,EIF4BB,DHX29,EIF1B,EIF4E,EIF6,EIF2A,BRF1A,EIF2B5 |
Interacting Protein
EIF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF1.
EPB41;OLFM2;RASA1;MAPK6;groL;q9wmx2-pro_0000037548
Resources
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References
- Moutaoufik, MT; El Fatimy, R; et al. UVC-Induced Stress Granules in Mammalian Cells. PLOS ONE 9:-(2014).
- Hamamura, K; Nishimura, A; et al. Salubrinal acts as a Dusp2 inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. CELLULAR SIGNALLING 27:828-835(2015).
