EFTUD2
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Official Full Name
elongation factor Tu GTP binding domain containing 2 -
Overview
116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene. -
Synonyms
EFTUD2;elongation factor Tu GTP binding domain containing 2;116 kDa U5 small nuclear ribonucleoprotein component;Snrp116;Snu114;U5 snRNP specific protein;116 kD;U5 116KD;hSNU114;U5-116 kDa;SNU114 homolog;U5 snRNP specific protein, 116 kD;U5 sn
Recombinant Proteins
- Zebrafish
- Human
- Chicken
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EFTUD2-10802Z | Recombinant Zebrafish EFTUD2 | Mammalian Cell | Zebrafish | His |
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| EFTUD2-3110H | Recombinant Human EFTUD2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EFTUD2-3147C | Recombinant Chicken EFTUD2 | Mammalian Cell | Chicken | His |
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| EFTUD2-6698HCL | Recombinant Human EFTUD2 293 Cell Lysate | HEK293 | Human | Non |
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| Eftud2-2758M | Recombinant Mouse Eftud2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EFTUD2-4252HF | Recombinant Full Length Human EFTUD2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 972 amino acids |
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| EFTUD2-559H | Recombinant Human EFTUD2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
EFTUD2 involved in several pathways and played different roles in them. We selected most pathways EFTUD2 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFTUD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | PLRG1,DHX38,SNRPB,PCBP1,DDX46,PRPF38B,HSPA1B,BAT1,AQR,PRP19 |
Protein Function
EFTUD2 has several biochemical functions, for example, GTP binding,GTPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFTUD2 itself. We selected most functions EFTUD2 had, and list some proteins which have the same functions with EFTUD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB22A,EEF1A2,MXB,TUBA8,RRAGC,RAB31,TUBA3E,CDC42,RAB11BB,DNM2A |
| protein binding | IFT172,DDX42,PGR,TRAF3,ITGB1BP2,SH2D4A,CTBP1,KTN1,MED18,GRHL2 |
| poly(A) RNA binding | EXOSC9,SEC23IP,APOBEC3C,NKRF,DHX57,STXBP1,POP1,SF3A1,TPR,LRP1 |
| GTP binding | SEPT7B,GNA15.1,RAB42B,KRAS,TUBA1C,RHOU,RAB1A,GBP3,RAB20,MXB |
| NOT translation elongation factor activity | GFM2 |
Interacting Protein
EFTUD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFTUD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFTUD2.
MYC;SNRNP40;SNW1;PRPF8;HSPB1;IK;SF3B4;DFFA;PTP4A3
Resources
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References
- Sato, N; Maeda, M; et al. Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. CANCER MEDICINE 4:268-277(2015).
- Gandomi, SK; Parra, M; et al. Array-CGH is an effective first-tier diagnostic test for EFTUD2-associated congenital mandibulofacial dysostosis with microcephaly. CLINICAL GENETICS 87:80-84(2015).
