EFCAB6
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Official Full Name
EF-hand calcium binding domain 6 -
Overview
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
EFCAB6;EF-hand calcium binding domain 6;EF-hand calcium-binding domain-containing protein 6;dJ185D5.1;DJBP;FLJ23588;HSCBCIP1;KIAA1672;CAP binding protein complex interacting protein 1;DJ1 binding protein;EF hand calcium binding domain 6;DJ-1-binding protein;CAP-binding protein complex-interacting protein 1
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EFCAB6-5016M | Recombinant Mouse EFCAB6 Protein | Mammalian Cell | Mouse | His |
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| EFCAB6-640HCL | Recombinant Human EFCAB6 cell lysate | Human | Non |
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| EFCAB6-1199H | Recombinant Human EFCAB6 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| EFCAB6-2660M | Recombinant Mouse EFCAB6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| EFCAB6-2660M-B | Recombinant Mouse EFCAB6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Efcab6-2745M | Recombinant Mouse Efcab6 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EFCAB6-4764H | Recombinant Human EFCAB6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
EFCAB6 involved in several pathways and played different roles in them. We selected most pathways EFCAB6 participated on our site, such as Androgen receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFCAB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Androgen receptor signaling pathway | RUNX2A,RNF6,PNRC1,PSMC3IP,PATZ1,SMAD3B,RAD9A,GNB2L1,DAXX,CTNNB1 |
Protein Function
EFCAB6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFCAB6 itself. We selected most functions EFCAB6 had, and list some proteins which have the same functions with EFCAB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | CANT1,MCFD2,PCDH2AB2,PKD1L3,OTOFA,MATN3,TLL1,BNIP2,CDH17,UBE4A |
Interacting Protein
EFCAB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFCAB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFCAB6.
Resources
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References
- Zhang, ZP; Xu, HX; et al. Schistosoma japonicum calcium-binding tegumental protein SjTP22.4 immunization confers praziquantel schistosomulumicide and antifecundity effect in mice. VACCINE 30:5141-5150(2012).
- Pico de Coana, Y; Parody, N; et al. Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonica. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 401:451-457(2010).
