EDARADD
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Official Full Name
EDAR (ectodysplasin-A receptor)-associated death domain -
Synonyms
cr;A630043P06;1810032E07Rik;5830469M23Rik
Recombinant Proteins
- Chicken
- Cynomolgus
- Human
- Mouse
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- His
- Myc&DDK
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EDARADD-1895C | Recombinant Chicken EDARADD | Mammalian Cell | Chicken | His |
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| EDARADD-477C | Recombinant Cynomolgus EDARADD Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| EDARADD-60H | Recombinant Human EDARADD Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| EDARADD-61H | Recombinant Human EDARADD Protein, GST-tagged | Wheat Germ | Human | GST |
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| EDARADD-6727HCL | Recombinant Human EDARADD 293 Cell Lysate | HEK293 | Human | Non |
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| EDARADD-223C | Recombinant Cynomolgus Monkey EDARADD Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| EDARADD-223C-B | Recombinant Cynomolgus Monkey EDARADD Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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| Edaradd-2724M | Recombinant Mouse Edaradd Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EDARADD-976HF | Recombinant Full Length Human EDARADD Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 215 amino acids |
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Involved Pathway
EDARADD involved in several pathways and played different roles in them. We selected most pathways EDARADD participated on our site, such as Cytokine Signaling in Immune system,Immune System,TNFR2 non-canonical NF-kB pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDARADD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNFs bind their physiological receptors | EDAR,EDA |
| Cytokine Signaling in Immune system | EIF4A1,TRIM31,FGF18B,NRG4,DPF1,DUSP4,KPNA3,TRIM68,RASGRP4,MARK3 |
| Immune System | GBP2,SIGLEC5,ALCAMB,TRIM46,SH3RF1,DEFB4A,DEFB103A,DDX41,DYNC1LI2,TRIM26 |
| TNFR2 non-canonical NF-kB pathway | EDAR,EDA |
Protein Function
EDARADD has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EDARADD itself. We selected most functions EDARADD had, and list some proteins which have the same functions with EDARADD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KLB,PIWIL1,PYDC1,RAP1GDS1,MT1A,CLUAP1,RAB33B,EPCAM,CTNNBIP1,PRKAA2 |
Interacting Protein
EDARADD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDARADD here. Most of them are supplied by our site. Hope this information will be useful for your research of EDARADD.
g2xkq0_human;SDCBP;SUMO1;UBE2I;TRAF2
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References
- Kuramoto, T; Yokoe, M; et al. A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene. BMC GENETICS 12:-(2011).
- van der Hout, AH; Oudesluijs, GG; et al. Mutation screening of the Ectodysplasin-A receptor gene EDAR in hypohidrotic ectodermal dysplasia. EUROPEAN JOURNAL OF HUMAN GENETICS 16:673-679(2008).
