Dgcr2
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Official Full Name
DGCR2 DiGeorge syndrome critical region gene 2 [ Homo sapiens ] -
Overview
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. -
Synonyms
DGS C;DGS2;DiGeorge syndrome critical region gene 2;IDD;integral membrane protein DGCR2;LAN;SEZ 12;DiGeorge syndrome critical region protein 2;integral membrane protein deleted in DiGeorge syndrome
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Mus musculus
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DGCR2-11950H | Recombinant Human DGCR2, GST-tagged | E.coli | Human | GST | N-term-300a.a. | |
| DGCR2-2564H | Recombinant Human DGCR2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DGCR2-4539M | Recombinant Mouse DGCR2 Protein | Mammalian Cell | Mouse | His |
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| DGCR2-766Z | Recombinant Zebrafish DGCR2 | Mammalian Cell | Zebrafish | His |
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| DGCR2-6964HCL | Recombinant Human DGCR2 293 Cell Lysate | HEK293 | Human | Non |
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| DGCR2-2346M | Recombinant Mouse DGCR2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DGCR2-2346M-B | Recombinant Mouse DGCR2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DGCR2-2492HF | Recombinant Full Length Human DGCR2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 550 amino acids |
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| RFL21010MF | Recombinant Full Length Mouse Integral Membrane Protein Dgcr2/Idd(Dgcr2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (25-548) |
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| RFL9764HF | Recombinant Full Length Human Integral Membrane Protein Dgcr2/Idd(Dgcr2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (21-550) |
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Involved Pathway
Dgcr2 involved in several pathways and played different roles in them. We selected most pathways Dgcr2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Dgcr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Dgcr2 has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Dgcr2 itself. We selected most functions Dgcr2 had, and list some proteins which have the same functions with Dgcr2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | CLEC4F,CLEC1A,NOMO1,CD34,KLRC1,PYGM,Clec4n,CLEC4A,KLRB1F,CLEC3B |
Interacting Protein
Dgcr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Dgcr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Dgcr2.
DDIT3;SMURF2
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