DYNC1I1
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Official Full Name
dynein, cytoplasmic 1, intermediate chain 1 -
Overview
Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene. -
Synonyms
DYNC1I1;dynein, cytoplasmic 1, intermediate chain 1;DNCI1, dynein, cytoplasmic, intermediate polypeptide 1;cytoplasmic dynein 1 intermediate chain 1;DNCIC1;DH IC-1;dynein intermediate chain 1, cytosolic;cytoplasmic dynein intermediate chain 1;dyn
Recombinant Proteins
- Rat
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DYNC1I1-1982R | Recombinant Rat DYNC1I1 Protein | Mammalian Cell | Rat | His |
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| DYNC1I1-2967H | Recombinant Human DYNC1I1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DYNC1I1-4945Z | Recombinant Zebrafish DYNC1I1 | Mammalian Cell | Zebrafish | His |
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| DYNC1I1-238HCL | Recombinant Human DYNC1I1 lysate | HEK293 | Human | Non |
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| DYNC1I1-1640R | Recombinant Rat DYNC1I1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DYNC1I1-1640R-B | Recombinant Rat DYNC1I1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Dync1i1-2695M | Recombinant Mouse Dync1i1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DYNC1I1-3293H | Recombinant Human DYNC1I1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| DYNC1I1-4142HF | Recombinant Full Length Human DYNC1I1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 628 amino acids |
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| DYNC1I1-5896H | Recombinant Human DYNC1I1 protein, His-tagged | Insect Cell | Human | His | 1-645aa |
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Involved Pathway
DYNC1I1 involved in several pathways and played different roles in them. We selected most pathways DYNC1I1 participated on our site, such as Adaptive Immune System,Immune System,MHC class II antigen presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNC1I1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | CTSC,IGHM,FBXO44,NA,SIGLEC11,RAET1E,CD160,LRRC41,DZIP3,DTX3L |
| Salmonella infection | DYNC1LI2,PFN4,IFNGR2,PKN1,NFKB1,ACTB1,RAB7A,MAPK12A,IL8L2,ROCK2 |
| Immune System | TAX1BP1,LAIR2,ABI2,SEC24A,PANX1A,PPAPDC1A,AP1G1,TRIM11,DDOST,GRAP2B |
| Phagosome | THBS4A,DYNC1I2A,BF1,SEC61AL2,TUBA3D,ATP6V0CA,RAB7A,MHC1UXA2,STX18,ITGB5 |
| MHC class II antigen presentation | CTSE,KLC3,CTSO,MGC174857,KIF11,KIF15,CTSH,AP1S3A,KIFAP3,FAM49BA |
Protein Function
DYNC1I1 has several biochemical functions, for example, microtubule binding,microtubule motor activity,motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNC1I1 itself. We selected most functions DYNC1I1 had, and list some proteins which have the same functions with DYNC1I1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| motor activity | DYNLL2,MYO1A,MYH9,CGNL1,MYH15,DYNLT1,MYL6B,SMYHC1,MYH11A,KIF18B |
| microtubule motor activity | KIF3B,KIF4A,DNAH5,SMC3,DYNLRB2,KIF4,KIF26A,KIFC1,DYNC1LI2,KIF20A |
| microtubule binding | ZFP207,KIF26A,LRPPRC,MARK4,KIF6,APC,KIF22,TRAF3IP1,MACF1,KIF15 |
| spectrin binding | SLC26A5,DCTN2,GBP1,UNC13A,STX4A,USH1G,MYO7A,CAMSAP1L1,GNB1,ADD2 |
| protein binding | RAB3C,STK39,CXCL9,MYO1E,C16orf45,TSSK4,DYRK1B,UBQLN2,BSCL2,GAS1 |
Interacting Protein
DYNC1I1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNC1I1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNC1I1.
Ccdc64;STAU1;TP53;SMAD2;Nde1;TUBB1;NUDT21;KAT7;TK1;FBP1;RCC1;ANXA7;MCC;CDKN1A;RAP1GAP;DNM2;PIN1
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References
- Ma, C; Yao, Y; et al. Differential Proteomic Analysis of Platelets Suggested Possible Signal Cascades Network in Platelets Treated with Salvianolic Acid B. PLOS ONE 6:-(2011).
- Cao, JJ; Lin, C; et al. Circovirus Transport Proceeds via Direct Interaction of the Cytoplasmic Dynein IC1 Subunit with the Viral Capsid Protein. JOURNAL OF VIROLOGY 89:2777-2791(2015).
