DTX3

  • Official Full Name

    deltex 3 homolog (Drosophila)
  • Overview

    DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
  • Synonyms

    DTX3;deltex 3 homolog (Drosophila);protein deltex-3;Deltex3;DTX3_HUMAN;Protein deltex 3;RING finger protein 154;RNF154;mDTX3;mg310

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DTX3-12192H Recombinant Human DTX3, His-tagged E.coli Human His 1-249a.a.
DTX3-2907H Recombinant Human DTX3 Protein, GST-tagged Wheat Germ Human GST
DTX3-4858M Recombinant Mouse DTX3 Protein Mammalian Cell Mouse His
DTX3-6793HCL Recombinant Human DTX3 293 Cell Lysate HEK293 Human Non
DTX3-1011H Recombinant Human DTX3 Protein (S2-D347), Tag Free E.coli Human Non S2-D347
DTX3-1012H Recombinant Human DTX3 Protein (S2-D347), GST tagged E.coli Human GST S2-D347
DTX3-2550M Recombinant Mouse DTX3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DTX3-2550M-B Recombinant Mouse DTX3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
DTX3-4069HF Recombinant Full Length Human DTX3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 347 amino acids

    Involved Pathway

    DTX3 involved in several pathways and played different roles in them. We selected most pathways DTX3 participated on our site, such as Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Notch signaling pathway JAG1A,CTBP1,ADAM17,MYCBP,HER15.1,MAML1,PSENEN,LNX1,NOTCH4,KAT2B

    Protein Function

    DTX3 has several biochemical functions, for example, ligase activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX3 itself. We selected most functions DTX3 had, and list some proteins which have the same functions with DTX3. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding UMPS,PDLIM5A,RNF122,RNF144B,CIZ1B,NR3C2,DHH,RNF144A,DPYS,ADAMTS15
    ligase activity TRAF3,WWP1,PET112L,MARCH10,RNF185,RING1,EGR2,COP1,RNF14,GATB
    protein binding IFT27,DARS2,CD14,RLTPR,ID3,SNAP91,BCLAF1,SH2D3C,CCNC,SH3PXD2B

    Interacting Protein

    DTX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX3.

    UBE2K;HIP2;UBE2L6;UBE2D1;UBE2E1;UBE2D3;UBE2H;UBE2D2;UBE2L3;XIAP;UBE2V1;ZDHHC17;UBE2DNL;UEVLD;RNF141;UBE2E3;UBE2W;UBE2E2

    Resources

    References

    • Konoki, K; Onoda, T; et al. In Vitro Acylation of Okadaic Acid in the Presence of Various Bivalves' Extracts. MARINE DRUGS 11:300-315(2013).
    • Gatza, ML; Silva, GO; et al. An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer. NATURE GENETICS 46:1051-1059(2014).

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