DSE
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Official Full Name
dermatan sulfate epimerase -
Overview
The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
DSE;dermatan sulfate epimerase;SART2, squamous cell carcinoma antigen recognized by T cells 2;dermatan-sulfate epimerase;DSEPI;Chondroitin glucuronate 5 epimerase;DS epimerase;OTTHUMP00000040406;SART 2;Squamous cell carcinoma antigen recognized by T cells 2;OTTHUMP00000017059;chondroitin-glucuronate 5-epimerase;squamous cell carcinoma antigen recognized by T-cells 2;DSEP;SART2;SART-2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DSE-2888H | Recombinant Human DSE Protein, GST-tagged | Wheat Germ | Human | GST |
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| DSE-3319Z | Recombinant Zebrafish DSE | Mammalian Cell | Zebrafish | His |
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| DSE-4837M | Recombinant Mouse DSE Protein | Mammalian Cell | Mouse | His |
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| DSE-511HCL | Recombinant Human DSE cell lysate | Human | Non |
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| DSE-1387H | Recombinant Human DSE Protein, His-tagged | E.coli | Human | His | Tyr23-His284 |
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| DSE-2536M | Recombinant Mouse DSE Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DSE-2536M-B | Recombinant Mouse DSE Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DSE-4253HF | Recombinant Full Length Human DSE Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 958 amino acids |
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Involved Pathway
DSE involved in several pathways and played different roles in them. We selected most pathways DSE participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ACSL4,ACADSB,LDHAL6A,ADC,MGAT2,PIK3C2G,PLD4,glpK,PTS,EPT1 |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | CHST15,CHPF,CHSY1,CSGALNACT2,CHST12A,CHSY3,CHST14,CHST3,B3GAT3,UST |
Protein Function
DSE has several biochemical functions, for example, chondroitin-glucuronate 5-epimerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DSE itself. We selected most functions DSE had, and list some proteins which have the same functions with DSE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chondroitin-glucuronate 5-epimerase activity | DSEL |
Interacting Protein
DSE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSE here. Most of them are supplied by our site. Hope this information will be useful for your research of DSE.
ACSL4;CPSF3L
Resources
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References
- Jenvey, CJ; Reichel, MP; et al. Investigation of the comparative sensitivity of serum, colostrum and whey for the detection of specific antibodies in sheep vaccinated against Johne's disease. SMALL RUMINANT RESEARCH 123:193-195(2015).
- Marciniuk, K; Maattanen, P; et al. Development of a Multivalent, PrPsc-Specific Prion Vaccine through Rational Optimization of Three Disease-Specific Epitopes. VACCINE 32:1988-1997(2014).
