DSC3
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Official Full Name
Desmocollin 3 -
Overview
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. -
Synonyms
DSC;DSC1;DSC2;DSC4;CDHF3;HT-CP;DSC3;desmocollin 3;desmocollin-3;desmocollin-4;cadherin family member 3;5430426I24Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DSC3-2881H | Recombinant Human DSC3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| Dsc3-1385M | Recombinant Mouse Dsc3 Protein, His-tagged | E.coli | Mouse | His | Arg136-Phe355 |
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| Dsc3-1386R | Recombinant Rat Dsc3 Protein, His-tagged | E.coli | Rat | His | Lys477-Lys695 |
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| Dsc3-2904M | Recombinant Mouse Dsc3 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Mouse | His | Full L. 136-896aa |
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| RFL14639SF | Recombinant Full Length Schizosaccharomyces Pombe Upf0645 Membrane Protein C20H4.02(Spac20H4.02) Protein, His-Tagged | E.coli expression system | Schizosaccharomyces pombe | His | Full L. Full Length (1-250) |
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Involved Pathway
DSC3 involved in several pathways and played different roles in them. We selected most pathways DSC3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DSC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DSC3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DSC3 itself. We selected most functions DSC3 had, and list some proteins which have the same functions with DSC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DSC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DSC3.
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References
- Aizawa, S; Ochiai, T; et al. Heterogeneous and abnormal localization of desmosomal proteins in oral intraepithelial neoplasms. JOURNAL OF ORAL SCIENCE 56:209-214(2014).
- Sezin, T; Avitan-Hersh, E; et al. Human Amnion Membrane as a Substrate for the Detection of Autoantibodies in Pemphigus Vulgaris and Bullous Pemphigoid. ISRAEL MEDICAL ASSOCIATION JOURNAL 16:217-223(2014).
