DPYSL4
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Official Full Name
dihydropyrimidinase-like 4 -
Overview
DRP-4 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as -
Synonyms
DPYSL4;dihydropyrimidinase-like 4;dihydropyrimidinase-related protein 4;DRP 4;ULIP4;CRMP-3;ULIP-4;UNC33-like phosphoprotein 4;collapsin response mediator protein 3;CRMP3;DRP-4
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- Mammalian cells
- HEK293
- HEK293T
- In Vitro Cell Free System
- His&T7
- His
- GST
- Non
- Flag
- Myc&DDK
- N-His-GST&C-V5-Myc
- His&Fc&Avi
Involved Pathway
DPYSL4 involved in several pathways and played different roles in them. We selected most pathways DPYSL4 participated on our site, such as Axon guidance,CRMPs in Sema3A signaling,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPYSL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Semaphorin interactions | SEMA3AB,SEMA3A,PLXND1,NRP1A,SEMA3AA,PLXNC1,CDK5R1B,DPYSL5A,DPYSL3,DPYSL2B |
| CRMPs in Sema3A signaling | DPYSL5B,DPYSL5A,CDK5,SEMA3AA,SEMA3AB,SEMA3A,DPYSL2,CRMP1,DPYSL3,NRP1A |
| Developmental Biology | FOXH1,KIF4A,GDF1,CACNG3,FGF20A,ACTR2B,ARPC1B,ST8SIA2,INSM1B,ARPC2 |
| Axon guidance | LAMTOR2,KLB,ROBO2,SRGAP2,NRAS,GFRA4,NRP1,PTK2,SPNA2,EFNB2 |
Protein Function
DPYSL4 has several biochemical functions, for example, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPYSL4 itself. We selected most functions DPYSL4 had, and list some proteins which have the same functions with DPYSL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | BTD,DPYSL5A,DPYSL2B,YDJC,CRMP1,DPYSL5B,NAAA,DPYSL5,DPYSL3 |
| protein binding | RALBP1,TRIM3,ASB6,KCNN4,ACLY,FAM109A,MAPK10,NOSTRIN,GAGE2D,EXOSC5 |
Interacting Protein
DPYSL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPYSL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPYSL4.
TRIP13;RBPMS;DPYSL2;PTPRO;SH3GL1;SH3GL2;SH3GL3
Resources
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References
- Doh, MS; Han, DMR; et al. Profiling of Proteins Regulated by Venlafaxine during Neural Differentiation of Human Cells. PSYCHIATRY INVESTIGATION 12:81-91(2015).
- Wang, J; Wang, J; et al. Proteomic analysis on infantile spasm and prenatal stress. EPILEPSY RESEARCH 108:1174-1183(2014).
