DPP3
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Official Full Name
dipeptidyl-peptidase 3 -
Overview
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized. -
Synonyms
DPP3;dipeptidyl-peptidase 3;dipeptidylpeptidase 3 , dipeptidylpeptidase III;dipeptidyl peptidase 3;Dipeptidyl aminopeptidase III;Dipeptidyl arylamidase III;Dipeptidyl peptidase III;DPP III;DPP3_HUMAN;EC 3.4.14.4;dipeptidylpeptidase 3;dipeptidylpeptidase III;DPPIII
Recombinant Proteins
- Mouse
- Rat
- Human
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- Sf9 Insect Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His&T7
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DPP3 involved in several pathways and played different roles in them. We selected most pathways DPP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DPP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DPP3 has several biochemical functions, for example, dipeptidyl-peptidase activity,metallopeptidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP3 itself. We selected most functions DPP3 had, and list some proteins which have the same functions with DPP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metallopeptidase activity | MMP23BB,ADAM10,MMP1A,ADAMTS15A,ADAM28,DNPEP,CLCA1,NPEPPS,ACY1,BRCC3 |
| protein binding | TGFA,RABGAP1,MAU2,EPHA2,ACAA1,PGAP2,PIK3R3,NDUFB10,ABCG1,BIRC3 |
| dipeptidyl-peptidase activity | DPEP3,DPP7,NAALAD2,FAP,DPEP2,DPEP1,DPP4,DPP8,PRCP |
| zinc ion binding | ZMAT2,BRCA1,POLR3K,VDR,TRIM72,ADAM7,PHRF1,FHL3,LIMK1A,JADE3 |
Interacting Protein
DPP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP3.
KEAP1;OSBPL10;HSPA8;ATP5C1;TERF1;TINF2;POT1;TERF2IP
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