DPF2
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Official Full Name
D4, zinc and double PHD fingers family 2 -
Overview
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. -
Synonyms
DPF2;D4, zinc and double PHD fingers family 2;REQ, requiem, apoptosis response zinc finger gene;zinc finger protein ubi-d4;ubi d4;BAF45D;protein requiem;BRG1-associated factor 45D;apoptosis response zinc finger protein;requiem, apoptosis respons
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
DPF2 involved in several pathways and played different roles in them. We selected most pathways DPF2 participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNF-alpha/NF-kB Signaling Pathway | PEG3,CAPN3,DCAF7,DDX3X,MARK2,FAF1,TIFA,G3BP2,TRPC4AP,USP2 |
Protein Function
DPF2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPF2 itself. We selected most functions DPF2 had, and list some proteins which have the same functions with DPF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | GLI2,KCNA3,TFAP2A,IFI16,SMAD2,FLI1,BCL11A,CTCFL,CEBPG,RELA |
| protein binding | DLG3,TES,CREM,EDDM3B,ZCCHC10,DPM1,BORA,RNF31,BMP10,SYCE3 |
| zinc ion binding | TRIM31,PYGO1,ADAMTS15A,BRF1,ADH8B,LONRF3,NANOS1,ADAMTSL1,MMP26,SETMAR |
Interacting Protein
DPF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPF2.
LDOC1;LNX1;RELB;Bcl7b;FHL2;q7ard3_yerpe;ZNF212;SYT-SSX1;Bcl7c;ID1;YAP1
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