DOK3
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Official Full Name
docking protein 3 -
Overview
Docking protein 3 is a protein that in humans is encoded by the DOK3 gene. -
Synonyms
DOK3;docking protein 3;FLJ22570;DOK 3;DOK Like Protein;DOK3_HUMAN;DOKL Pending;Downstream of tyrosine kinase 3;p62 DOK Like Protein;Dok-like protein;DOKL
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293T
- HEK293
- In Vitro Cell Free System
- His
- His&GST
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
DOK3 involved in several pathways and played different roles in them. We selected most pathways DOK3 participated on our site, such as B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DOK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | LYN,PPP3R1,NRAS,CTNNB2,Cd79a,BANK1,TTC6,RAF1,PPP3CA,PIK3R1 |
Protein Function
DOK3 has several biochemical functions, for example, insulin receptor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DOK3 itself. We selected most functions DOK3 had, and list some proteins which have the same functions with DOK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KISS1,ZNF488,RHNO1,HP1BP3,CXCL11,MYOCD,VAC14,SUPV3L1,Fzd4,RNF175 |
| insulin receptor binding | DOK1B,INSL3,IRS1,PIK3R1,SNX4,PDPK1,SNX1,DOK2,IGF1,LMBRD1 |
Interacting Protein
DOK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOK3.
TRAF1;RBPMS;GRB2;INPP5D;o68740_yerpe;q7chq0_yerpe;yjhB;GRB2;BLNK
Resources
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References
- Braun, MC; Herring, SM; et al. Hypertensive Renal Injury Is Associated With Gene Variation Affecting Immune Signaling. CIRCULATION-CARDIOVASCULAR GENETICS 7:903-U421(2014).
- Ou, XJ; Xu, SL; et al. Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:11431-11436(2014).
