DNM3
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Official Full Name
dynamin 3 -
Overview
Members of the dynamin family, such as DNM3, possess mechanochemical properties involved in actin-membrane processes,;predominantly in membrane budding (Orth and McNiven, 2003 (PubMed 12517701)). -
Synonyms
DNM3;dynamin 3;dynamin-3;Dyna III;KIAA0820;testicular;DNM 3;DNM3 protein;Dyn3;DYN3_HUMAN;DynaIII;dynamin 2;Dynamin;Dynamin family member;Dynamin testicular;Dynamin3;EC 3.6.5.5;MGC70433;T dynamin;T-dynamin;dynamin, testicular
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DNM3-12106H | Recombinant Human DNM3, His-tagged | E.coli | Human | His | 206-555a.a. | |
| DNM3-1925R | Recombinant Rat DNM3 Protein | Mammalian Cell | Rat | His |
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| DNM3-4738M | Recombinant Mouse DNM3 Protein | Mammalian Cell | Mouse | His |
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| DNM3-6856HCL | Recombinant Human DNM3 293 Cell Lysate | HEK293 | Human | Non |
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| DNM3-1584R | Recombinant Rat DNM3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DNM3-1584R-B | Recombinant Rat DNM3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DNM3-2075H | Recombinant Human DNM3 Protein (Met1-Thr323), N-His tagged | E.coli | Human | His | Met1-Thr323 |
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| Dnm3-242M | Recombinant Mouse Dnm3 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DNM3-2471M | Recombinant Mouse DNM3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DNM3-2471M-B | Recombinant Mouse DNM3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
DNM3 involved in several pathways and played different roles in them. We selected most pathways DNM3 participated on our site, such as Phospholipase D signaling pathway,Endocytosis,Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocrine and other factor-regulated calcium reabsorption | PRKACG,KLK1B11,PLCB4,ATP1A4,KLK1B8,ATP1A3,KLK1B22,PLCB1,ATP1A2,KL |
| Phospholipase D signaling pathway | PPAP2A,PLCB1,PLA2G4A,AKT2,GRM3,PDGFD,LPAR5,GRM1,CXCR1,INS2 |
| Endocytosis | PLD2,CSF1R,EEA1,EPN1,DNM2,D6WSU116E,RAB11FIP4,HSP70L,CAV3,ADRBK2 |
| Synaptic vesicle cycle | ATP6V0A2,ATP6V1A,NSF,ATP6V0B,ATP6V1G1,RIMS1,STX3,STX2,SLC17A7,ATP6V1D |
| Bacterial invasion of epithelial cells | SEPT3,RHOA,ARPC5,ACTB,PIK3CA,WASL,CRK,DNM1,ARPC5L,ARPC2 |
Protein Function
DNM3 has several biochemical functions, for example, GTP binding,GTPase activity,nitric-oxide synthase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNM3 itself. We selected most functions DNM3 had, and list some proteins which have the same functions with DNM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nitric-oxide synthase binding | SNTA1,ACTB,ATP2B4,CAV3,CD74,CALM3,CALM2,DMD,CALM1,SLC6A4 |
| protein binding | UBA1,NUS1,PLAT,BRD4,ATG4A,DDX6,EXD1,CGA,LBR,UQCRC2 |
| type 5 metabotropic glutamate receptor binding | HOMER1,ADORA2A |
| GTP binding | TUBA3D,ATL2,GBP2,RHOAA,IRGC,GNAI2,GNAI2A,RAB42,OLA1,RHOBTB2 |
| GTPase activity | TUBD1,TUBA1B,RALBA,DDX3X,RRAGA,RAB42B,RALAA,GNAV1,RAB3DB,GNL1 |
Interacting Protein
DNM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNM3.
FNBP1;a8k1f4_human;ABL1;FYN;HSF2;PSMD2;FKBP5;NUDCD3;q96be0_human;TTC1;PPP5C;AARSD1;CACYBP;FKBPL;STUB1;15-deoxy-delta(12,14;AMPH;GRB2;SH3GL1
DNM3 Related Signal Pathway
Resources
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References
- Chowdhury, SM; Manepalli, P; et al. Graphene nanoribbons elicit cell specific uptake and delivery via activation of epidermal growth factor receptor enhanced by human papillomavirus E5 protein. ACTA BIOMATERIALIA 10:4494-4504(2014).
- Lee, ST; Ji, H; et al. Global protein profiling reveals anti-EGFR monoclonal antibody 806-modulated proteins in A431 tumor xenografts. GROWTH FACTORS 31:154-164(2013).
