DNAJB12
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Official Full Name
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 [ Homo sapiens ] -
Overview
DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). -
Synonyms
DJ10;DJB12_HUMAN;DKFZp586B2023;DnaJ (Hsp40) homolog, subfamily B, member 12;DnaJ homolog subfamily B member 12;Dnajb12
Recombinant Proteins
- Human
- Chicken
- Mouse
- Bovine
- Mus musculus
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DNAJB12 involved in several pathways and played different roles in them. We selected most pathways DNAJB12 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJB12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | TUSC3,SEC13,AMFR,ATXN3,EIF2AK4,SAR1A,PDIA6,LMAN1L,SEC24B,FBXO2 |
Protein Function
DNAJB12 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJB12 itself. We selected most functions DNAJB12 had, and list some proteins which have the same functions with DNAJB12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DNAJB12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJB12 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJB12.
Resources
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References
- Goodwin, EC; Motamedi, N; et al. Expression of DNAJB12 or DNAJB14 Causes Coordinate Invasion of the Nucleus by Membranes Associated with a Novel Nuclear Pore Structure. PLOS ONE 9:-(2014).
- Walczak, CP; Ravindran, MS; et al. A Cytosolic Chaperone Complexes with Dynamic Membrane J-Proteins and Mobilizes a Nonenveloped Virus out of the Endoplasmic Reticulum. PLOS PATHOGENS 10:-(2014).
