DNAAF1
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Official Full Name
dynein, axonemal, assembly factor 1 -
Overview
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13. -
Synonyms
DNAAF1;dynein, axonemal, assembly factor 1;leucine rich repeat containing 50 , LRRC50;dynein assembly factor 1, axonemal;CILD13;FLJ25330;ODA7;outer row dynein assembly 7 homolog (Chlamydomonas);leucine rich repeat containing 50;outer row dynein a
Recombinant Proteins
- Human
- Rat
- Mouse
- Zebrafish
- Mammalian Cell
- HEK293
- HEK293T
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DNAAF1 involved in several pathways and played different roles in them. We selected most pathways DNAAF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DNAAF1 has several biochemical functions, for example, dynein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAAF1 itself. We selected most functions DNAAF1 had, and list some proteins which have the same functions with DNAAF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| dynein binding | NEFH,KATNA1,SNCA,ATMIN,PAFAH1B1,WDR43,KATNB1,WDR81,DCTN6,PAFAH1B1A |
Interacting Protein
DNAAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAAF1.
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