DHX32
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Official Full Name
DEAH (Asp-Glu-Ala-His) box polypeptide 32 -
Overview
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. -
Synonyms
DHX32;DEAH (Asp-Glu-Ala-His) box polypeptide 32;DDX32, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 32;putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32;DHLP1;FLJ10694;FLJ10889;Ddx32;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32;3110079L04Rik;AA408140;DEAD/H box 32;DEAD/H helicase like protein 1;DEAH box protein 32;Helicase DDX32;HuDDX32;OTTHUMP00000020717;OTTHUMP00000020718;DEAD/H helicase-like protein 1;DEAD/H helicase-like protein-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DHX32-11985H | Recombinant Human DHX32, GST-tagged | E.coli | Human | GST | C-term-352a.a. | |
| DHX32-2608H | Recombinant Human DHX32 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DHX32-4575M | Recombinant Mouse DHX32 Protein | Mammalian Cell | Mouse | His |
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| DHX32-6930HCL | Recombinant Human DHX32 293 Cell Lysate | HEK293 | Human | Non |
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| Dhx32-181M | Recombinant Mouse Dhx32 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DHX32-2365M | Recombinant Mouse DHX32 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DHX32-2365M-B | Recombinant Mouse DHX32 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DHX32-2552HF | Recombinant Full Length Human DHX32 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 743 amino acids |
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| DHX32-5271H | Recombinant Human DHX32 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
DHX32 involved in several pathways and played different roles in them. We selected most pathways DHX32 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DHX32 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX32 itself. We selected most functions DHX32 had, and list some proteins which have the same functions with DHX32. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | UGP2,SDC1,FOXK2,NCSTN,SYNJ2BP,DYX1C1,CREB5,ELN,UBA6,SRGAP2 |
| ATP-dependent RNA helicase activity | DDX10,DHX8,DDX39,EIF4A1A,DDX3,DHX30,BAT1,G3BP1,DHX38,DDX21 |
| ATP binding | SLC22A5,Adcy4,MMAB,ABCC3,PRKACBA,RRM1,ADCY1,ATP1A1A.2,INO80,DCLK1A |
| poly(A) RNA binding | RBMS2,WDR3,RPP30,PTCD2,PURA,HIST1H1D,MTDH,TBCA,ABT1,SNIP1 |
Interacting Protein
DHX32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX32 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX32.
FAM161A;rpoB
Resources
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References
- Huang, CL; Liang, XM; et al. Up-regulation and clinical relevance of novel helicase homologue DHX32 in colorectal cancer. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 28:-(2009).
- Alli, Z; Ho, M; et al. Characterization of murine Dhx32. EXPERIMENTAL AND MOLECULAR PATHOLOGY 83:115-118(2007).
