DHX16
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Official Full Name
DEAH (Asp-Glu-Ala-His) box polypeptide 16 -
Overview
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
DHX16;DEAH (Asp-Glu-Ala-His) box polypeptide 16;DDX16, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 16;putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16;DBP2;Prp2;PRPF2;2410006N22Rik;ATP-dependent RNA helicase 3;DAQB-47P19.12;DBP 2;DDX 16;DDX16;DEAH box protein;DEAH box protein 16;DEAH-box protein;fa91b12;KIAA0577;mKIAA0577;PRO2014;PRP 8;PRP8;wu:fa91b12;zgc:55590;RNA helicase;DEAD/H box 16;OTTHUMP00000029071;DEAH-box protein 16;ATP-dependent RNA helicase #3;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DHX16-10382Z | Recombinant Zebrafish DHX16 | Mammalian Cell | Zebrafish | His |
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| DHX16-1262R | Recombinant Rhesus monkey DHX16 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| DHX16-2607H | Recombinant Human DHX16 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DHX16-476HCL | Recombinant Human DHX16 cell lysate | Human | Non |
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| DHX16-1087R | Recombinant Rhesus Macaque DHX16 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| DHX16-1087R-B | Recombinant Rhesus Macaque DHX16 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Dhx16-2555M | Recombinant Mouse Dhx16 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
DHX16 involved in several pathways and played different roles in them. We selected most pathways DHX16 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SRSF6B,MAGOH2,TXNL4A,SRSF5,EFTUD2,CRNKL1,SNRPA,SRSF4,TRA2A,HNRNPA1L2 |
Protein Function
DHX16 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX16 itself. We selected most functions DHX16 had, and list some proteins which have the same functions with DHX16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RWDD2B,ABHD16A,PPM1K,HSPB1,FZR1,DUSP21,SERBP1,PPP4R2,LEPROT,RPS18 |
| ATP-dependent RNA helicase activity | DDX41,CHST13,DDX51,DDX20,DDX39,DDX19B,EIF4A3,DDX49,DDX55,BAT1 |
| poly(A) RNA binding | TIAL1,XRN1,RRP1,ZRANB2,ARHGEF1,CNOT4,NOM1,HIST1H4M,NMD3,SUB1 |
| ATP binding | PAK2,PPP2R4,TOP2A,HIPK1,EHD3,KIF6,ABCA4A,TAOK3,PRKD3,HSC70 |
| RNA helicase activity | DHX9,FAM120B,RAD54B,SKIV2L2,DDX17,CTU1,CCDC111,UAP1L1,DDX10,DDX24 |
Interacting Protein
DHX16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX16 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX16.
SF3B2;DHX38;GPKOW;XAB2;CSNK2A1;Bud13;COIL;DGCR14;MEGF10;ssrna_ug;VCAM1
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