DEPDC6
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Official Full Name
DEP domain containing MTOR-interacting protein -
Overview
DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene. -
Synonyms
DEP.6;DEPDC6;FLJ12341;FLJ12428;FLJ13854;DKFZp564B1778;DEP domain-containing mTOR-interacting protein;OTTHUMP00000228295;OTTHUMP00000228296;DEP domain containing 6;DEP domain-containing protein 6;DEP domain containing mTOR interacting protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DEPDC6-4348C | Recombinant Chicken DEPDC6 | Mammalian Cell | Chicken | His |
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| DEPDC6-6973HCL | Recombinant Human DEPDC6 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
DEPDC6 involved in several pathways and played different roles in them. We selected most pathways DEPDC6 participated on our site, such as Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met),mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DEPDC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mTOR signaling pathway | INS,PDPK1,EIF4BB,PRKCG,PIK3R1,RRAGCB,PIK3R3B,RPS6KB1,EIF4E1C,RPS6KA6 |
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | MUC20 |
Protein Function
DEPDC6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DEPDC6 itself. We selected most functions DEPDC6 had, and list some proteins which have the same functions with DEPDC6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BLVRA,NECAB2,SIX4,ZSCAN16,ABCB1,DNAJB11,IKBKB,SMAD4,CBX8,F8 |
Interacting Protein
DEPDC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEPDC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEPDC6.
RICTOR;RPTOR;TRAF1;CCDC110;MTOR;Mtor
Resources
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References
- Davies, J; Zachariades, E; et al. Elucidating the role of DEPTOR in Alzheimer's disease. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:1195-1200(2014).
- Caron, A; Baraboi, ED; et al. DEP Domain-Containing mTOR-Interacting Protein in the Rat Brain: Distribution of Expression and Potential Implication. JOURNAL OF COMPARATIVE NEUROLOGY 523:93-107(2015).
