DDX42
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 -
Overview
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. -
Synonyms
DDX42;DEAD (Asp-Glu-Ala-Asp) box polypeptide 42;ATP-dependent RNA helicase DDX42;RHELP;RNAHP;SF3b125;DEAD box polypeptide 42 protein;DEAD box protein 42;EC 3.6.1.-;FLJ43179;RNA helicase-like protein;RNA helicase-related protein;SF3b DEAD-box protein;SF3b125 DEAD-box protein;Splicing factor 3B-associated 125 kDa protein;SF3b DEAD box protein
Recombinant Proteins
- Rhesus macaque
- Human
- Chicken
- Zebrafish
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DDX42-1219R | Recombinant Rhesus monkey DDX42 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| DDX42-2490H | Recombinant Human DDX42 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DDX42-2615C | Recombinant Chicken DDX42 | Mammalian Cell | Chicken | His |
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| DDX42-3601Z | Recombinant Zebrafish DDX42 | Mammalian Cell | Zebrafish | His |
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| DDX42-4419M | Recombinant Mouse DDX42 Protein | Mammalian Cell | Mouse | His |
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| DDX42-456HCL | Recombinant Human DDX42 cell lysate | Human | Non |
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| DDX42-1044R | Recombinant Rhesus Macaque DDX42 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| DDX42-1044R-B | Recombinant Rhesus Macaque DDX42 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| DDX42-2273M | Recombinant Mouse DDX42 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DDX42-2273M-B | Recombinant Mouse DDX42 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DDX42-2604HF | Recombinant Full Length Human DDX42 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 819 amino acids |
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Involved Pathway
DDX42 involved in several pathways and played different roles in them. We selected most pathways DDX42 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SRSF2B,MAGOH2,SNW1,SFRS9,TCERG1A,CDC40,RBM17,DHX38,PRPF40B,TCERG1 |
Protein Function
DDX42 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX42 itself. We selected most functions DDX42 had, and list some proteins which have the same functions with DDX42. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CSNK2A2,MAPK13,XRCC2,CDK16,NUBPL,HSPD1,DNAJA3A,FRK,KITB,TTF2 |
| ATP-dependent RNA helicase activity | TDRD12,DDX3X,DDX27,DDX39B,DDX23,EIF4A1,DDX3,DDX20,DDX59,DDX25 |
| poly(A) RNA binding | APOBEC3F,EIF4B,CCDC137,HIST1H1B,RPS3A,HSD17B10,ILF2,HIST1H4B,MYH9,PEBP1 |
| protein binding | AQP1,DDI1,TWF2,FBXO6,MPZL1,GUCY1B3,PMS2,MAPK12,CLIC2,NKD1 |
Interacting Protein
DDX42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX42 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX42.
SF3A2;Sf3a1;U2SURP;DHX15;RECQL5;SNRPC;recX;SF3B4;SF3A1;anmK;PRPF19;Aff1;Kifc5b;Kif13b;ssrna_ug;Itgb1;VCAM1
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