DDX10
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -
Overview
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. -
Synonyms
DDX10;DEAD (Asp-Glu-Ala-Asp) box polypeptide 10;DEAD/H (Asp Glu Ala Asp/His) box polypeptide 10 (RNA helicase);probable ATP-dependent RNA helicase DDX10;HRH J8;DEAD box-10;DEAD box protein 10;DDX10-NUP98 fusion protein type 2;DEAD/H (Asp-Glu-Ala-A
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DDX10-11889H | Recombinant Human DDX10, GST-tagged | E.coli | Human | GST | 100-431a.a. | |
| DDX10-2463H | Recombinant Human DDX10 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DDX10-3558C | Recombinant Chicken DDX10 | Mammalian Cells | Chicken | His |
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| DDX10-4398M | Recombinant Mouse DDX10 Protein | Mammalian Cells | Mouse | His |
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| DDX10-2262M | Recombinant Mouse DDX10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DDX10-2262M-B | Recombinant Mouse DDX10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DDX10-2528HF | Recombinant Full Length Human DDX10 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 875 amino acids |
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Involved Pathway
DDX10 involved in several pathways and played different roles in them. We selected most pathways DDX10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DDX10 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX10 itself. We selected most functions DDX10 had, and list some proteins which have the same functions with DDX10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | EIF5,FNDC3A,SF1,ZFC3H1,MRPL10,KTN1,DCAF13,RPL36,TCP1,YTHDC2 |
| ATP-dependent RNA helicase activity | DDX31,DDX24,DDX19,DQX1,DDX6,DDX17,DDX21,DHX38,UPF1,DDX3Y |
| ATP binding | FUK,UBE2IB,ENPP1,ACSS1,PAICS,ACOT12,DNAJA4,ATP2C2,SYN1,FGFR2 |
| RNA helicase activity | FAM120B,CHST13,DDX24,CCDC111,UAP1L1,CTU1,DHX9,DHX15,DDX5,DDX6 |
Interacting Protein
DDX10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX10 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX10.
G3BP2;NOP56;EED;MNDA;IFI16;Tmod3
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