DDO
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Official Full Name
D-aspartate oxidase -
Overview
The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
DDO;D-aspartate oxidase;D aspartate oxidase;DASOX;DDO 1;DDO 2;FLJ45203;OTTHUMP00000017000;aspartic oxidase;D-aspartate oxidase, DDO;DDO-1;DDO-2
Recombinant Proteins
- Human
- Mouse
- Cattle
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cell
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
Involved Pathway
DDO involved in several pathways and played different roles in them. We selected most pathways DDO participated on our site, such as Alanine, aspartate and glutamate metabolism,Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alanine, aspartate and glutamate metabolism | ADSSL,GAD2,IL4I1,ALDH4A1,FOLH1,GOT2,ASL2,ASPA,GLUD1B,PPAT |
| Peroxisome | CROT,ACAA1A,SLC25A17,PEX13,DAO.3,SCP2,ECH1,AGXTA,MPV17,PEX5 |
Protein Function
DDO has several biochemical functions, for example, D-aspartate oxidase activity,FAD binding,cofactor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDO itself. We selected most functions DDO had, and list some proteins which have the same functions with DDO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | PVRL1A,CXCL10,HNF4A,HAO1,Ifnl2,Artn,PPY,TAC3,AMACR,DAO |
| cofactor binding | PGAM2,HIF1AN,HACL1,TKT,WWOX,ACLY,TYMS,C3,DAO,LMO2 |
| protein binding | KCNMA1,NARG1,C11orf65,AKAP5,KDM5A,PINK1,NRG1,NPHP4,C7orf42,IYD |
| FAD binding | MTRR,DAO.3,COQ6,AGPS,MICAL1,CRY2,DAO1,DAO.2,CYB5R3,DAO.1 |
Interacting Protein
DDO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDO here. Most of them are supplied by our site. Hope this information will be useful for your research of DDO.
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