DCDC2
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Official Full Name
doublecortin domain containing 2 -
Overview
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
DCDC2;doublecortin domain containing 2;doublecortin domain-containing protein 2;DCDC2A;KIAA1154;RU2;DCDC 2;DCDC2_HUMAN;HGNC:18141;Protein RU2S;RU2S;RU2S protein;OTTHUMP00000017887
Recombinant Proteins
- Rat
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DCDC2-1792R | Recombinant Rat DCDC2 Protein | Mammalian Cell | Rat | His |
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| DCDC2-2389H | Recombinant Human DCDC2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DCDC2-7052HCL | Recombinant Human DCDC2 293 Cell Lysate | HEK293 | Human | Non |
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| DCDC2-1450R | Recombinant Rat DCDC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DCDC2-1450R-B | Recombinant Rat DCDC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DCDC2-2799HF | Recombinant Full Length Human DCDC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 476 amino acids |
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| DCDC2-301165H | Recombinant Human DCDC2 protein, GST-tagged | E.coli | Human | GST | Glu351-Ala476 |
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| DCDC2-3063H | Recombinant Human DCDC2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
DCDC2 involved in several pathways and played different roles in them. We selected most pathways DCDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DCDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DCDC2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCDC2 itself. We selected most functions DCDC2 had, and list some proteins which have the same functions with DCDC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NHP2L1,TREML1,PTK7,OS9,USP47,SPG11,SDHA,KRT16,DNMBP,TMEM147 |
Interacting Protein
DCDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DCDC2.
NIF3L1;MRFAP1
Resources
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References
- Truong, DT; Che, A; et al. Mutation of Dcdc2 in mice leads to impairments in auditory processing and memory ability. GENES BRAIN AND BEHAVIOR 13:802-811(2014).
- Inokawa, Y; Nomoto, S; et al. Detection of doublecortin domain-containing 2 (DCDC2), a new candidate tumor suppressor gene of hepatocellular carcinoma, by triple combination array analysis. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 32:-(2013).
