DBX2
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Official Full Name
developing brain homeobox 2 -
Overview
Members of the Dbx family are implicated in regionalization of the CNS. Dbx2 is restricted to the ventricular region of the embryonic CNS as well as some of the mesenchymal cells, such as limb buds and tooth germs. BMP regulation of the expression boundaries of the homeobox proteins Dbx2, Pax6 and Msx1 generates precursor populations with distinct developmental potentials. -
Synonyms
DBX2;developing brain homeobox 2;Gm1229;AI846217;9630005K15;9430056A22Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DBX2-2378H | Recombinant Human DBX2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DBX2-4708C | Recombinant Chicken DBX2 | Mammalian Cell | Chicken | His |
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| Dbx2-2468M | Recombinant Mouse Dbx2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DBX2-2716HF | Recombinant Full Length Human DBX2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 339 amino acids |
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| DBX2-6440H | Recombinant Human DBX2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| DBX2-979H | Recombinant Human DBX2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
DBX2 involved in several pathways and played different roles in them. We selected most pathways DBX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DBX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DBX2 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DBX2 itself. We selected most functions DBX2 had, and list some proteins which have the same functions with DBX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | MKXA,RAX2,NANOG,HOXB6,DLX2A,NR6A1,BARHL1A,HOXC9A,FOXO1A,EF1 |
Interacting Protein
DBX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DBX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DBX2.
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References
- Hambright, D; Park, KY; et al. Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina. MOLECULAR VISION 18:920-936(2012).
- Itoh, M; Takizawa, Y; et al. Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: Consideration of pancreas differentiation. DIFFERENTIATION 80:118-122(2010).
