DBP
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Official Full Name
D site of albumin promoter (albumin D-box) binding protein -
Overview
The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific;sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as;a homo- or heterodimer and is involved in the regulation of some circadian rhythym genes. -
Synonyms
DBP;D site of albumin promoter (albumin D-box) binding protein;D site-binding protein;DABP;Albumin D box-binding protein;Albumin D-element-binding protein;DBP_HUMAN;Tax-responsive enhancer element-binding protein 302;TAXREB302;TRANSCRIPTION FACTOR DBP
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- HAdV-5
- Human adenovirus C serotype 2
- Human adenovirus 5
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Insect Cell
- In Vitro Cell Free System
- HEK293F
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
DBP involved in several pathways and played different roles in them. We selected most pathways DBP participated on our site, such as BMAL1:CLOCK,NPAS2 activates circadian gene expression,Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with DBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | CRY1,NAMPT,CREBBP,NCOA2,CARM1,CRY2,NRIP1,HELZ2 |
| Circadian Clock | CRY1,RAI1,CSNK1E,NRIP1,NAMPT,HELZ2,CARM1,CRY2,CPT1A |
Protein Function
DBP has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DBP itself. We selected most functions DBP had, and list some proteins which have the same functions with DBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TCF21,ETV6,BATF,EBF4,FOXJ2,FOXK2,CAMTA2,ONECUTL,ZFAT,EGR1 |
| RNA polymerase II regulatory region sequence-specific DNA binding | E2F7,ZNF549,BARHL1A,FOXF2,TFAP2D,RARG,POU3F4,MYOG,PURB,POGZA |
Interacting Protein
DBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DBP here. Most of them are supplied by our site. Hope this information will be useful for your research of DBP.
DDIT3;Clock;HLF
Resources
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References
- Derosa, G; Romano, D; et al. The effects of canrenone on inflammatory markers in patients with metabolic syndrome. ANNALS OF MEDICINE 47:47-52(2015).
- Yokota, H; Nagaoka, T; et al. Serum prorenin levels are not associated with ocular diseases in non-diabetic subjects. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM 16:153-158(2015).
