DAK
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Official Full Name
dihydroxyacetone kinase 2 homolog (S. cerevisiae) -
Overview
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4,5-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. -
Synonyms
DAK;dihydroxyacetone kinase 2 homolog (S. cerevisiae);dihydroxyacetone kinase 2 homolog (yeast);bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);DKFZP586B1621;NET45;ATP dependent dihydroxyacetone kinase;Bifunctional ATP dependent dihydroxyacetone kinase/FAD AMP lyase (cyclizing);DHA kinase;Dha kinase/FMN cyclase;DHAK_HUMAN;Dihydroxyacetone kinase;Dihydroxyacetone kinase 2;FAD AMP lyase (cyclic FMN forming);FAD AMP lyase (cyclizing);FAD-AMP lyase (cyclic FMN forming);FAD-AMP lyase (cyclizing);FMN cyclase;Glycerone kinase;OTTHUMP00000235855;OTTHUMP00000235860;FAD-AMP lyase cyclizing;FAD-AMP lyase cyclic FMN forming;ATP-dependent dihydroxyacetone kinase
Recombinant Proteins
- Human
- Rat
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DAK-11819H | Recombinant Human DAK, GST-tagged | E.coli | Human | GST | C-term-350a.a. | |
| DAK-1771R | Recombinant Rat DAK Protein | Mammalian Cell | Rat | His |
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| DAK-4299M | Recombinant Mouse DAK Protein | Mammalian Cell | Mouse | His |
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| DAK-4520Z | Recombinant Zebrafish DAK | Mammalian Cell | Zebrafish | His |
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| DAK-2112HCL | Recombinant Human DAK cell lysate | Human | Non |
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| DAK-1429R | Recombinant Rat DAK Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DAK-1429R-B | Recombinant Rat DAK Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DAK-2196M | Recombinant Mouse DAK Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DAK-2196M-B | Recombinant Mouse DAK Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
DAK involved in several pathways and played different roles in them. We selected most pathways DAK participated on our site, such as Glycerolipid metabolism,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | ALDH2,DGKD,LPIN2,LIPG,DGKZ,PNLIPRP3,CEL.1,AKR1A1B,MBOAT1,ALDH9A1B |
| Metabolic pathways | ASAH1B,CYP2R1,DPM3,NMNAT1,IPMK,ACOT2,FPGS,POLR3K,ybaS,DNMT3A |
| Carbon metabolism | ESD,MUT,IDH3B,OGDHL,TKT,H6PD,ACADS,GOT1,HK1,PKM2 |
| RIG-I-like receptor signaling pathway | IL-8,MAPK8,OTUD5A,TANK,ATG5,PL10,MAVS,NFKBIAA,RNF207B,IFNW1 |
Protein Function
DAK has several biochemical functions, for example, ATP binding,FAD-AMP lyase (cyclizing) activity,glycerone kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DAK itself. We selected most functions DAK had, and list some proteins which have the same functions with DAK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | STOML1,C16orf5,NEUROD1,PSMD7,TCEANC,ATXN7,ADAMTS4,TATDN1,AHCY,RAD9B |
| ATP binding | CDKL4,MAP4K5,PGK2,AKT2L,PC,GAK,NDUFA13,HSPA12A,PRKCD,CDK2 |
| metal ion binding | HIC2,RNFT1,ZNF773,PPP3CC,KDM5BA,SUMF2,ZNFX1,TRIM27,KEX2,ACAP3B |
Interacting Protein
DAK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAK here. Most of them are supplied by our site. Hope this information will be useful for your research of DAK.
SDCBP;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate
Resources
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References
- Reid, ME; Hipsky, CH; et al. The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL. TRANSFUSION 53:539-544(2013).
- Borrisholt, M; Nielsen, S; et al. Demonstration of CDX2 is Highly Antibody Dependant. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 21:64-72(2013).
