Cux2
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Official Full Name
CUX2 cut-like homeobox 2 [ Homo sapiens (human) ] -
Overview
This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. -
Synonyms
CDP2;Cut like homeobox 2;Cut-like 2;CUTL2;Cux2;CUX2_HUMAN;Homeobox protein cut-like 2;Homeobox protein cux 2;Homeobox protein Cux-2;KIAA0293
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CUX2-11710H | Recombinant Human CUX2, GST-tagged | E.coli | Human | GST | 110-433a.a. | |
| CUX2-2614H | Recombinant Human CUX2 protein, His-tagged | E.coli | Human | His | 110-433 aa | |
| CUX2-1004H | Recombinant Human CUX2 | Mammalian Cell | Human | His |
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| CUX2-2140H | Recombinant Human CUX2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CUX2-4085M | Recombinant Mouse CUX2 Protein | Mammalian Cell | Mouse | His |
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| CUX2-2085M | Recombinant Mouse CUX2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CUX2-2085M-B | Recombinant Mouse CUX2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CUX2-2757H | Recombinant Human CUX2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| CUX2-2757H-B | Recombinant Human CUX2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
Cux2 involved in several pathways and played different roles in them. We selected most pathways Cux2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Cux2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
Cux2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cux2 itself. We selected most functions Cux2 had, and list some proteins which have the same functions with Cux2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | ZGPAT,ZFP90,NR2E1,DACH1,NFE2L3,TCF3,NKX6-1,PROX2,NFATC4,HMGA2 |
| RNA polymerase II regulatory region sequence-specific DNA binding | ZIK1,RARA,SKINT8,AIRE,LYL1,STOX1,LMO2,GFI1AA,POGZA,BARX1 |
| sequence-specific DNA binding | ETV5A,GRHL2,DBPA,FLI1B,IRX7,SOX21B,ZFP423,GATAD2AB,SATB1A,EN1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | MEF2A,KLF5,CEBPG,TCF12,JUN,TCF7L2,POU2F3,NR3C1,FUBP3,SKIL |
Interacting Protein
Cux2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cux2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cux2.
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