Cox7a2
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Official Full Name
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) [ Homo sapiens ] -
Overview
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. -
Synonyms
COX7A2;COX7AL;COX7AL1;COXVIIa L;COXVIIAL;CX7A2_HUMAN;Cytochrome c oxidase polypeptide 7A2 mitochondrial;Cytochrome c oxidase polypeptide VIIa liver/heart;Cytochrome c oxidase subunit 7A2;Cytochrome c oxidase subunit 7A2 mitochondrial;Cytochrome c oxidase subunit VIIa polypeptide 2;Cytochrome c oxidase subunit VIIa-L;Cytochrome c oxidase subunit VIIa-liver/heart;Cytochrome c oxidase subunit VIIaL;Hepatic cytochrome c oxidase chain VIIa;MGC118950;MGC118951;MGC118952;MGC126875;MGC126877;mitochondrial;VIIAL
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COX7A2-11500H | Recombinant Human COX7A2, GST-tagged | E.coli | Human | GST | 1-83a.a. | |
| COX7A2-12H | Recombinant Human COX7A2 protein, GST-tagged | Wheat Germ | Human | GST | 1-56 a.a. |
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| COX7A2-3823M | Recombinant Mouse COX7A2 Protein | Mammalian Cell | Mouse | His |
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| COX7A2-4224C | Recombinant Chicken COX7A2 | Mammalian Cell | Chicken | His |
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| COX7A2-7326HCL | Recombinant Human COX7A2 293 Cell Lysate | HEK293 | Human | Non |
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| COX7A2-1920M | Recombinant Mouse COX7A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| COX7A2-1920M-B | Recombinant Mouse COX7A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Cox7a2 involved in several pathways and played different roles in them. We selected most pathways Cox7a2 participated on our site, such as Alzheimers disease,Cardiac muscle contraction,Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cox7a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alzheimers disease | ATP5E,APH1B,COX6B1,NDUFB10,ATP2A1,NDUFA3,NDUFB3,CALM4,COX5A,UQCR11 |
| Non-alcoholic fatty liver disease (NAFLD) | MAPK9,COX7B,NDUFS1,Fasl,COX7B2,PRKAA2,SDHC,PIK3R1,UQCRFS1,INS |
| Huntingtons disease | DNALC1,SLC25A4,GRIN2B,COX4I1,UQCRC2,CASP8,COX7B,NDUFA4L2,TAF4B,COX8A |
| Electron Transport Chain | COX5B,SURF1,COX11,COX4I1,COX6A1,COX8A,COX6B1,SLC25A27,UCP2,ATP5L |
| Oxidative phosphorylation | ATP6V0C,NDUFS2,ATP6V1F,COX4I2,ATP6V1A,ATP6V0D1,NDUFS4,NDUFS6,NDUFA6,ATP6V1G2 |
| Parkinsons disease | COX6A2,COX7A2L,NDUFA10,NDUFA13,PRKACA,NDUFAB1,NDUFB5,Atp5g2,NDUFS4,UBE2L3 |
| Cardiac muscle contraction | CACNG4,UQCRFS1,CACNG3,ACTC1A,ATP1B2B,UQCRC1,CACNG2A,ATP2A2,CACNB3A,COX5B2 |
Protein Function
Cox7a2 has several biochemical functions, for example, cytochrome-c oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cox7a2 itself. We selected most functions Cox7a2 had, and list some proteins which have the same functions with Cox7a2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytochrome-c oxidase activity | COX7A2A,COX15,COX7C,COX6A2,COX6B2,COA6,SURF1,COX5A,COX6B1,COX5AA |
Interacting Protein
Cox7a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cox7a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cox7a2.
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