Cd180
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Official Full Name
CD180 antigen -
Overview
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail.;The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex,;RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in;concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of;Gram-negative bacteria. -
Synonyms
CD180;CD180 antigen;ly-78;lymphocyte antigen 78;radioprotective 105 kDa protein;Ly78;RP105;F630107B15
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- HEK293
- Insect Cell
- Human Cell
- Mammalian cells
- His
- Non
- Fc
- hIgG4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CD180-10915H | Recombinant Human CD180, His-tagged | E.coli | Human | His | C-term-348a.a. | |
| CD180-1598R | Recombinant Rhesus Monkey CD180 Protein | HEK293 | Rhesus macaque | Non | 24-626 a.a. | |
| Cd180-3305M | Recombinant Mouse Cd180 protein, His-tagged | HEK293 | Mouse | His | Met1-Ser626 | |
| CD180-3900H | Recombinant Human CD180 protein, His-tagged | HEK293 | Human | His | Met1-Gly626 | |
| CD180-3064H | Recombinant Human CD180 protein, His-tagged | E.coli | Human | His | 164-389 aa | |
| CD180-1599R | Recombinant Rhesus Monkey CD180 Protein, hIgG1-tagged | HEK293 | Rhesus macaque | Fc | 24-626 a.a. |
|
| CD180-1600R | Recombinant Rhesus Monkey CD180 Protein, hIgG4-tagged | HEK293 | Rhesus macaque | hIgG4 | 24-626 a.a. |
|
| Cd180-3260M | Recombinant Mouse Cd180 protein, hFc-tagged | HEK293 | Mouse | Fc | Met1-Ser626 |
|
| Cd180-3261M | Recombinant Mouse Cd180 protein, Fc-tagged | Insect Cell | Mouse | Fc | Thr21 - Ser626 |
|
| CD180-2099HCL | Recombinant Human CD180 cell lysate | Human Cell | Human | Non |
|
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| CD180-2224MCL | Recombinant Mouse CD180 cell lysate | Human Cell | Mouse | Non |
|
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| CD180-2225MCL | Recombinant Mouse CD180 cell lysate | Human Cell | Mouse | Non |
|
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| CD180-096H | Recombinant Human CD180 Protein, C-His-tagged | E.coli | Human | His |
|
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| CD180-1396H | Recombinant Human CD180 Protein (Thr430-Gly626), N-His tagged | E.coli | Human | His | Thr430-Gly626 |
|
| CD180-4475H | Recombinant Human CD180 Protein (Met1-Gly626), C-His tagged | Mammalian cells | Human | His | Met1-Gly626 |
|
| CD180-655H | Recombinant Human CD180 Protein, His-tagged | E.coli | Human | His | Asp288-Asp620 |
|
Involved Pathway
Cd180 involved in several pathways and played different roles in them. We selected most pathways Cd180 participated on our site, such as Immune System,Innate Immune System,Toll Like Receptor 4 (TLR4) Cascade, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd180 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toll Like Receptor 4 (TLR4) Cascade | SIGIRR,LY86 |
| Toll-Like Receptors Cascades | CNPY3,UNC93B1,LY86,TNRC5,CTS7 |
| Immune System | NLRP4E,POLR3H,CLEC2D,GBP6,DEFA3,SIGLEC6,IFITM2,KLRB1F,CYLD,CASP4 |
| Innate Immune System | TXNIPA,POLR3H,FCN1,NOD1,NLRP4,BTR16,DHX9,CASP2,TAX1BP1B,TRIM56 |
Protein Function
Cd180 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Cd180 itself. We selected most functions Cd180 had, and list some proteins which have the same functions with Cd180. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
Cd180 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd180 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd180.
Resources
Research Area
Immune Regulatory Molecules on Endothelial CellsB Cell CD Antigen
Monocyte Markers
Thymus-Independent B Cell Activation
Dendritic Cell Pathogen Recognition/Uptake
Related Services
Related Products
References
- Huang, PY; Best, OG; et al. Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia. LEUKEMIA & LYMPHOMA 55:2085-2092(2014).
- Karper, JC; de Jager, SCA; et al. An Unexpected Intriguing Effect of Toll-Like Receptor Regulator RP105 (CD180) on Atherosclerosis Formation With Alterations on B-Cell Activation. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 33:2810-2817(2013).
