CYP4A22
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Official Full Name
cytochrome P450, family 4, subfamily A, polypeptide 22 -
Overview
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. -
Synonyms
CYP4A22;cytochrome P450, family 4, subfamily A, polypeptide 22;cytochrome P450 4A22;CYPIVA22;Cytochrome P450 4A22K;Cytochrome P450 family 4 subfamily A polypeptide 22;Fatty acid omega hydroxylase;Lauric acid omega hydroxylase;RP1 18D14.1;fatty acid omega-hydroxylase;lauric acid omega-hydroxylase
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Involved Pathway
CYP4A22 involved in several pathways and played different roles in them. We selected most pathways CYP4A22 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4A22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
CYP4A22 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4A22 itself. We selected most functions CYP4A22 had, and list some proteins which have the same functions with CYP4A22. You can find most of the proteins on our site.
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Interacting Protein
CYP4A22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4A22 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4A22.
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References
- Woillard, JB; Kamar, N; et al. Effect of CYP3A4*22, POR*28, and PPARA rs4253728 on Sirolimus In Vitro Metabolism and Trough Concentrations in Kidney Transplant Recipients. CLINICAL CHEMISTRY 59:1761-1769(2013).
- Efstathiou, E; Titus, M; et al. Molecular Characterization of Enzalutamide-treated Bone Metastatic Castration-resistant Prostate Cancer. EUROPEAN UROLOGY 67:53-60(2015).
