CYP27C1
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Official Full Name
cytochrome P450, family 27, subfamily C, polypeptide 1 -
Overview
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. -
Synonyms
CYP27C1;cytochrome P450, family 27, subfamily C, polypeptide 1;cytochrome P450 27C1;FLJ16008;Cytochrome P450 family 27 subfamily C polypeptide 1;Cytochrome P450 family 27 subfamily C polypeptide 13;cytochrome P450, family 27, subfamily C, polypeptide 13
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CYP27C1-6281Z | Recombinant Zebrafish CYP27C1 | Mammalian Cell | Zebrafish | His |
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| CYP27C1-3392H | Recombinant Human CYP27C1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
CYP27C1 involved in several pathways and played different roles in them. We selected most pathways CYP27C1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP27C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CYP27C1 has several biochemical functions, for example, heme binding,iron ion binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP27C1 itself. We selected most functions CYP27C1 had, and list some proteins which have the same functions with CYP27C1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion binding | CYP19A1,TMEM195,CYP1C2,AOX4,FTL,CYP2K17,CYP2A12,CYP3C1L2,P4HA1B,FDX1 |
| heme binding | CYP4F18,CYP2F2,CYP46A1.3,CYP2A13,MPX,CYP2P9,CYP2W1,CYP2AA6,CYP2P6,CYP4T8 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | CYP46A1.2,CYP2A12,CYP4A10,P4HA1A,CYP2P9,CYP2V1,CYP2D26,CYP2Y3,CYP2X8,CYP1A |
| oxidoreductase activity | NOS2B,CYP2AA1,DHRS13L1,RDH1,OSGIN2,CYP2A12,GPD1B,CREG1,CYP3A25,CYP2C54 |
| monooxygenase activity | CYP3C1L2,BCMO1,CYP46A1.1,CYP26C1,CYP2K18,CYP2K22,MOXD2,CYP2B6,TYR,CYP1A4 |
| metal ion binding | NFS1,LEPREL1,ZNF384L,HERC2,NRXN1,TRIM41,TMPPE,ZNF7,CYP39A1,RHEBL1 |
Interacting Protein
CYP27C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP27C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP27C1.
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References
- Spokoyny, I; Barazangi, N; et al. Reduced Clopidogrel Metabolism in a Multiethnic Population: Prevalence and Rates of Recurrent Cerebrovascular Events. JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 23:694-698(2014).
- Bremmer, F; Thelen, P; et al. Expression and Function of the Vitamin D Receptor in Malignant Germ Cell Tumour of the Testis. ANTICANCER RESEARCH 32:341-349(2012).
