CUL9
-
Official Full Name
cullin 9 -
Overview
Cytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity. -
Synonyms
CUL9;PARC;H7AP1;RP3-330M21.2;DKFZp686G1042;DKFZp686P2024;Human p53-associated, Parkin-like Cytoplasmic protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CUL9-1452H | Recombinant Human CUL9 protein, His & GST-tagged | E.coli | Human | His&GST | Ile1144~Ala1322 |
|
| CUL9-7179HCL | Recombinant Human CUL9 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
CUL9 involved in several pathways and played different roles in them. We selected most pathways CUL9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CUL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CUL9 has several biochemical functions, for example, ATP binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CUL9 itself. We selected most functions CUL9 had, and list some proteins which have the same functions with CUL9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EIF1AX,DBC1,AOC3,TLR2,Raet1a,NPAS2,MSR1,SP1,PDPK1,GTF2IRD2 |
| ATP binding | BMPR2A,Atp8a2,NLRP7,PGK1,PRKAG3,DNAJA2,TWF1,PMS1,KIF3B,PRPS1L1 |
| ubiquitin protein ligase binding | AXIN2,EGR2,HM13,BCL2,STUB1,CUL5,UBE2J2,CUL3,TP53,RANGAP1 |
| zinc ion binding | CBLC,TRIM109,DTNA,SEC24C,CA4B,MLLT6,ADAT3,RNF4,ADAM19,TRIM9 |
Interacting Protein
CUL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CUL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of CUL9.
TP53;Klc1;SRC;ysuB;q8d015_yerpe;PLXNB3;S4;MAP1LC3B
Resources
Related Services
Related Products
References
- Gama, V; Swahari, V; et al. The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells. SCIENCE SIGNALING 7:-(2014).
- Lopez, J; Tait, SWG; et al. Killing the Killer: PARC/CUL9 Promotes Cell Survival by Destroying Cytochrome c. SCIENCE SIGNALING 7:-(2014).
