CUL5
-
Official Full Name
cullin 5 -
Overview
Cullin-5 is a protein that in humans is encoded by the CUL5 gene. -
Synonyms
CUL5;cullin 5;VACM1;VACM-1;cullin-5;CUL-5;OTTHUMP00000232740;OTTHUMP00000232742;Vasopressin-activated calcium-mobilizing receptor-1;vasopressin-activated calcium-mobilizing receptor 1;Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1)
Recombinant Proteins
- Human
- Rat
- Mouse
- Insect Cell
- Sf21 insect cells
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Non
- His
- GST
- His&Strep
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CUL5 involved in several pathways and played different roles in them. We selected most pathways CUL5 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CUL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | HERC4,UBE2G1B,TRIM37,CBLC,TRIM32,KLHL13,FANCL,FZR1A,UBE3A,UBE2D2L |
Protein Function
CUL5 has several biochemical functions, for example, calcium channel activity,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CUL5 itself. We selected most functions CUL5 had, and list some proteins which have the same functions with CUL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | USP25,GABARAP,UBE2A,DERL1,DAXX,AKTIP,RPA3,PRKAR1A,MFN2,UQCRC1 |
| calcium channel activity | CACNA1DA,PSEN1,TPCN1,PKD2L1,CACNG2A,ITPR1,CHRNA9,GRIN3A,TRPC4A,ITPR3 |
| contributes_to ubiquitin protein ligase activity | CUL1B,CUL4B,FBXL15,CUL3,C10orf46,CUL5A,FBXL7,FBXL14,FBXL6,CUL4A |
| receptor activity | PVR,NOTCH4,GRIN2A,CD5,NLGN4Y,CLEC4M,NLGN3,LILRA2,CADM2A,CADM1B |
| protein binding | RXRA,IL6,VPS37A,MOCOS,CBX4,PPIB,CNTNAP2,RASSF2,EDEM1,PPP1R2P9 |
| protein heterodimerization activity | PRPH,PIK3R2,HIST3H3,BOK,PEF1,TENM1,HIST1H4J,HEXB,PPP2R4,MEF2A |
Interacting Protein
CUL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CUL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CUL5.
RNF7;RBX1;ARIH2;CCNDBP1
Resources
Related Services
Related Products
References
- Zhao, K; Du, J; et al. Evolutionarily conserved pressure for the existence of distinct G2/M cell cycle arrest and A3H inactivation functions in HIV-1 Vif. CELL CYCLE 14:838-847(2015).
- Bulatov, E; Martin, EM; et al. Biophysical Studies on Interactions and Assembly of Full-size E3 Ubiquitin Ligase SUPPRESSOR OF CYTOKINE SIGNALING 2 (SOCS2)-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 (RBX2). JOURNAL OF BIOLOGICAL CHEMISTRY 290:4178-4191(2015).
