CTSA
-
Official Full Name
cathepsin A -
Overview
This gene encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CTSA;cathepsin A;GSL, PPGB, protective protein for beta galactosidase (galactosialidosis);lysosomal protective protein;carboxypeptidase C;BETA GALACTOSIDASE PROTECTIVE PROTEIN;EC 3.4.16.5;Glactosialidosis;GLB2;Goldberg Syndrome;GSL;NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION;NGBE;PPCA;PPGB;Protective protein for beta galactosidase;OTTHUMP00000031778;OTTHUMP00000031780;OTTHUMP00000031781;carboxypeptidase L;beta-galactosidase 2;protective protein cathepsin A;beta-galactosidase protective protein
Recombinant Proteins
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- Cattle
- Dog
- Human
- Pig
- Rat
- Hamster
- HEK293
- Mammalian Cell
- Insect Cell
- E.coli
- Human Cell
- CHO
- Mammalian cells
- HEK293T
- His
- His&GST
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CTSA involved in several pathways and played different roles in them. We selected most pathways CTSA participated on our site, such as Lysosome,Renin-angiotensin system, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Renin-angiotensin system | KLK1B22,ACE,CPA3,Ren1,CMA1,KLK1B5,KLK1B24,NLN,KLK2,AGTR1B |
| Lysosome | AGA,ASAH1,LAPTM5,SORT1B,AP3S2,LIPA,PPT2,GALCB,Abca2,CTSC |
Protein Function
CTSA has several biochemical functions, for example, carboxypeptidase activity,enzyme activator activity,serine-type carboxypeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSA itself. We selected most functions CTSA had, and list some proteins which have the same functions with CTSA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type carboxypeptidase activity | CPVL,CPD,DPP7,CPE,CPM,SENP2,CPDB,CPZ,PRCP,SCPEP1 |
| enzyme activator activity | MGST2,CASP9,CTAGE5,DNMT3L,APOA5,SLX4,CFLAR,PRKCE,ALOX5AP,CLPSL1 |
| carboxypeptidase activity | CNDP1,AGBL1,CPA2,NAALAD2,BLMH,AGBL4,CPE,NAALADL1,ACE2,CNDP2 |
Interacting Protein
CTSA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSA here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSA.
CTNNBIP1;tktA;pepP;vacB;carB;pi3p;GABARAP;ELN;GABARAPL2;Bcas2;GABARAPL1;VAPA
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