CRYBA4

  • Official Full Name

    crystallin, beta A4

  • Overview

    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the;major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens;central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout;life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma;families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided;into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting;peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the;C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of;different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins.;This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.

  • Synonyms

    CRYBA4;crystallin, beta A4;beta-crystallin A4;Beta A4 crystallin;Beta crystallin A4;Beta-A4 crystallin;CRBA4_HUMAN;Crystallin beta A4;Eye lens structural protein;lens structural protein

Recombinant Proteins

  • Rat
  • Human
  • Zebrafish
  • Chicken
  • Mammalian Cells
  • Wheat Germ
  • E.coli
  • Human
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CRYBA4-1612R Recombinant Rat CRYBA4 Protein Mammalian Cells Rat His
CRYBA4-1931H Recombinant Human CRYBA4 Protein, GST-tagged Wheat Germ Human GST
CRYBA4-2640Z Recombinant Zebrafish CRYBA4 Mammalian Cells Zebrafish His
CRYBA4-3607H Recombinant Human CRYBA4, His-tagged E.coli Human His
CRYBA4-4987H Recombinant Human Crystallin, Beta A4, His-tagged Human Human His
CRYBA4-5752C Recombinant Chicken CRYBA4 Mammalian Cells Chicken His
CRYBA4-7263HCL Recombinant Human CRYBA4 293 Cell Lysate HEK293 Human Non
CRYBA4-1270R Recombinant Rat CRYBA4 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CRYBA4-1270R-B Recombinant Rat CRYBA4 Protein Pre-coupled Magnetic Beads HEK293 Rat
CRYBA4-2131HF Recombinant Full Length Human CRYBA4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 196 amino acids
CRYBA4-301499H Recombinant Human CRYBA4 protein, GST-tagged E.coli Human GST Met1-Val44

    Involved Pathway

    CRYBA4 involved in several pathways and played different roles in them. We selected most pathways CRYBA4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CRYBA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    CRYBA4 has several biochemical functions, for example, molecular_function,protein binding,structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by CRYBA4 itself. We selected most functions CRYBA4 had, and list some proteins which have the same functions with CRYBA4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ZHX2,PCTP,NCS1,PROM1,ANK2,ALDH3B1,ST8SIA5,CAB39L,UQCRH,TBL1X
    structural constituent of eye lens CRYGN1,ASL1,CRYGS,HSPB6,CRYGN2,LIM2.1,CRYGC,CRYGB,LIM2,LIM2.4
    molecular_function TPRG,GM2002,RPRMA,TMEM246,CRYBA2,FAM107A,PRB4,HSF5,EDDM3B,NRSN2

    Interacting Protein

    CRYBA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRYBA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRYBA4.

    CEP76;CRYBB2;CRYBB1

    Resources

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