CRTAP
-
Official Full Name
cartilage associated protein -
Overview
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. -
Synonyms
CRTAP;cartilage associated protein;cartilage-associated protein;CASP;leprecan like 3;LEPREL3;leprecan-like 3;OI7
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CRTAP involved in several pathways and played different roles in them. We selected most pathways CRTAP participated on our site, such as Collagen biosynthesis and modifying enzymes,Collagen formation,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRTAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Collagen formation | COL28A1D,ADAMTS2,TLL2,TLL1,COL13A1,COL1A1,MMP13,COL11A1B,CTSB,PCOLCEB |
| Extracellular matrix organization | P3H2,MGC174857,COL23A1,MMP13,LAMB1B,TLL1,MATN3,COL9A1,LOXL1,LTBP2 |
| Collagen biosynthesis and modifying enzymes | COL2A1,COL5A3B,COL1A2,COL5A2,ADAMTS2,COL9A1B,EMID2,COL5A1,PCOLCE2,COL4A4 |
Protein Function
CRTAP has several biochemical functions, for example, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRTAP itself. We selected most functions CRTAP had, and list some proteins which have the same functions with CRTAP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | IST1,ATG101,ING2,SHANK1,ABI1,CDK4,ABP1,EPCAM,RANBP2,TELO2 |
Interacting Protein
CRTAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRTAP here. Most of them are supplied by our site. Hope this information will be useful for your research of CRTAP.
Sf3a1;WDR48;NUDT21;VPS26A;cona_canen;RNPS1;Srsf1;FIP1L1
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