CRB2
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Official Full Name
crumbs homolog 2 (Drosophila) -
Synonyms
CRB2;crumbs homolog 2 (Drosophila);18688;ENSG00000148204;RP11-230L22.2;9q33.3;FLJ16786, FLJ38464;crumbs homolog 2;crumbs homolog 2;crumbs-like protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CRB2-3881M | Recombinant Mouse CRB2 Protein | Mammalian Cell | Mouse | His |
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| CRB2-1960M | Recombinant Mouse CRB2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CRB2-1960M-B | Recombinant Mouse CRB2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CRB2 involved in several pathways and played different roles in them. We selected most pathways CRB2 participated on our site, such as Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hippo signaling pathway | BMP6,DLG3,AXIN2,PPP2CA,BMP5,CCND2,ITGB2L,NKD1,BTRC,FZD10 |
Protein Function
CRB2 has several biochemical functions, for example, contributes_to aspartic-type endopeptidase inhibitor activity,calcium ion binding,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRB2 itself. We selected most functions CRB2 had, and list some proteins which have the same functions with CRB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | ECM1,ZFP36,AXIN2,BIRC7,PTPLAD2,TAF10,GSTM4,CTNNB1,CALU,PEX7 |
| calcium ion binding | NOX5,NCALD,ITPR3,EFCC1,SPTAN1,PPP3R1,S100S,PCDH2G1,ANXA10,SULF2 |
Interacting Protein
CRB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRB2.
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References
- Ebarasi, L; Ashraf, S; et al. Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS 96:153-161(2015).
- Slavotinek, A; Kaylor, J; et al. CRB2 Mutations Produce a Phenotype Resembling Congenital Nephrosis, Finnish Type, with Cerebral Ventriculomegaly and Raised Alpha-Fetoprotein. AMERICAN JOURNAL OF HUMAN GENETICS 96:162-169(2015).
